Recombinant human BCL7A protein | NKMAX ATGP1854 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human BCL7A protein

catalog :

ATGP1854

quantity :

4 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human BCL7A protein

Domain :

1-210aa

Catalog number (SKU) :

ATGP1854

NCBI :

NP_001019979

Description :

BCL7A is directly involved, with Myc and IgH, in a three-way gene translocation in a Burkitt lymphoma cell line. As a result of the gene translocation, the N-terminal region of the gene is disrupted, which is thought to be related to the pathogenesis of a subset of high-grade B cell non-Hodgkin lymphoma. The N-terminal segment involved in the translocation includes the region that shares a strong sequence similarity with those of BCL7B and BCL7C. Two transcript variants encoding different isoforms have been found for this gene. Recombinant human BCL7A protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Alternative Names :

B-cell CLL/lymphoma 7 protein family member A, BCL7

Concentration :

0.25mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT, 2mM EDTA

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Carbone,A., et al. (2008) Genes Chromosomes Cancer 47 (12), 1067-1075;; Morton,L.M., et al. (2009) Cancer Epidemiol. Biomarkers Prev. 18 (4), 1259-1270;;

Purity :

> 85% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Metabolism

Molecular Weight :

25.2 kDa (233aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)

Amino Acid Sequence :

MGSSHHHHHH SSGLVPRGSH MGSMSGRSVR AETRSRAKDD IKRVMAAIEK VRKWEKKWVT VGDTSLRIYK WVPVTEPKVD DKNKNKKKGK DEKCGSEVTT PENSSSPGMM DMHDDNSNQS SIADASPIKQ ENSSNSSPAP EPNSAVPSDG TEAKVDEAQA DGKEHPGAED ASDEQNSQSS MEHSMNSSEK VDRQPSGDSG LAAETSAISQ DLEGVPPSKK MKLEASQQNS EEM

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

Q4VC05

Internal Search Terms :

BCL7A, B-cell CLL/lymphoma 7 protein family member A, BCL7,ATGP1854-10ug,ATGP1854-20ug,ATGP1854-50ug,ATGP1854-100ug,ATGP1854-250ug,ATGP1854-500ug,ATGP1854-1mg,ATGP1854-10,ATGP1854-20,ATGP1854-50,ATGP1854-100,ATGP1854-250,ATGP1854-500,ATGP1854-1

more info or order :

NKMAX product webpage