Recombinant human PARD6B protein | NKMAX ATGP1840 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human PARD6B protein

catalog :

ATGP1840

quantity :

4 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human PARD6B protein

Domain :

1-372aa

Catalog number (SKU) :

ATGP1840

NCBI :

NP_115910

Description :

Partitioning defective 6 homolog beta, also known as PARD6B, is a member of the PAR6 family and encodes a protein with a PSD95/Discs-large/ZO1 (PDZ) domain, an OPR domain and a semi-Cdc42/Rac interactive binding (CRIB) domain. Cellular asymmetry is critical for the development of multicellular organisms. PARD (partitioning-defective) proteins play important roles in asymmetric cell division and polarized growth, whereas Cdc42 and Rac mediate establishment of cell growth and polarity and contribute to oncogenic transformation by Ras. It is expressed in pancreas and in both adult and fetal kidney, and is weakly expressed in placenta and lung. Recombinant human PARD6B protein, fused to His-tag at N-terminus, was expressed in E. coli.

Alternative Names :

Partitioning defective 6 homolog beta, PAR6B

Concentration :

0.5mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 2M urea, 20% glycerol, 0.2M NaCl

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Joberty G., et al. (2000) Nat Cell Biol. 2:531-539.;; Qiu R G., et al. (2000) Curr Biol. 10:697-707.;;

Purity :

> 85% by SDS-PAGE

Applications :

SDS-PAGE,Denatured

Antigen Species :

Human

Gene Category :

Cell Cycle

Molecular Weight :

43.6 kDa (395aa)

Amino Acid Sequence :

MGSSHHHHHH SSGLVPRGSH MGSMNRSHRH GAGSGCLGTM EVKSKFGAEF RRFSLERSKP GKFEEFYGLL QHVHKIPNVD VLVGYADIHG DLLPINNDDN YHKAVSTANP LLRIFIQKKE EADYSAFGTD TLIKKKNVLT NVLRPDNHRK KPHIVISMPQ DFRPVSSIID VDILPETHRR VRLYKYGTEK PLGFYIRDGS SVRVTPHGLE KVPGIFISRL VPGGLAQSTG LLAVNDEVLE VNGIEVSGKS LDQVTDMMIA NSRNLIITVR PANQRNNVVR NSRTSGSSGQ STDNSLLGYP QQIEPSFEPE DEDSEEDDII IEDNGVPQQI PKAVPNTESL ESLTQIELSF ESGQNGFIPS NEVSLAAIAS SSNTEFETHA PDQKLLEEDG TIITL

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

Q9BYG5

Internal Search Terms :

PARD6B, Partitioning defective 6 homolog beta, PAR6B,ATGP1840-10ug,ATGP1840-20ug,ATGP1840-50ug,ATGP1840-100ug,ATGP1840-250ug,ATGP1840-500ug,ATGP1840-1mg,ATGP1840-10,ATGP1840-20,ATGP1840-50,ATGP1840-100,ATGP1840-250,ATGP1840-500,ATGP1840-1

more info or order :

NKMAX product webpage