protein

Recombinant human HES7 protein

ATGP1838

20 ug

80 USD

Recombinant human HES7 protein

1-230aa

ATGP1838

NP_001159439

HES7 is a member of the hairy and enhancer of split family of bHLH transcription factors. The mouse ortholog of this gene is regulated by Notch signaling. The protein functions as a transcriptional repressor, and is implicated in correct patterning of the axial skeleton. A mutation in this gene has been shown to result in spondylocostal dysostosis. Multiple transcript variants encoding different isoforms have been found for this gene. Recombinant human HES7 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Transcription factor HES-7, Hairy and enhancer of split 7; bHLHb37; SCDO4

1mg/ml (determined by Bradford assay)

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Sparrow DB, et al. (2008). Hum Mol Genet. 1;;17(23):3761-6.;; Sillence D, et al. (2010). Eur J Hum Genet. 18(6):674-9.;;

> 85% by SDS-PAGE

SDS-PAGE, Denatured

Human

Ubiquitination

27 kDa (253aa)

MVTRDRA ENRDGPKMLK PLVEKRRRDR INRSLEELRL LLLERTRDQN LRNPKLEKAE ILEFAVGYLR ERSRVEPPAA AAPGVPRSPV QDAEALASCY LSGFRECLLR LAAFAHDASP AARAQLFSAL HGYLRPKPPR PKPVDPRPPA PRPSLDPAAP ALGPALHQRP PVHQGHPSPR CAWSPSLCSP RAGDSGAPAP LTGLLPPPPP PHRQDGAPKA PLPPPPAFWR PWP

His-Tag

E.coli

Recombinant Protein

Q9BYE0

HES7, Transcription factor HES-7, Hairy and enhancer of split 7; bHLHb37; SCDO4,ATGP1838-10ug,ATGP1838-20ug,ATGP1838-50ug,ATGP1838-100ug,ATGP1838-250ug,ATGP1838-500ug,ATGP1838-1mg,ATGP1838-10,ATGP1838-20,ATGP1838-50,ATGP1838-100,ATGP1838-250,ATGP1838-500,ATGP1838-1