Recombinant human DTD1 protein | NKMAX ATGP1831 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human DTD1 protein

catalog :

ATGP1831

quantity :

4 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human DTD1 protein

Domain :

1-209aa

Catalog number (SKU) :

ATGP1831

NCBI :

NP_543010

Description :

DTD1 hydrolyzes D-tyrosyl-tRNA (Tyr) into D-tyrosine and free tRNA (Tyr). It could be a defense mechanism against a harmful effect of D-tyrosine. DTD1 may be a risk factor for aspirin-intolerant asthma (AIA) by catalyzing the hydrolysis of D-tryptophan and interacting with the tyrosyl-tRNA synthetase (tyrRS) enzyme, which promotes a pro-inflammatory phenotype. This protein is localize to the DuE (DNA unwinding element ) s of active replication origins. Recombinant human DTD1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Alternative Names :

D-tyrosyl-tRNA deacylase 1, bA379J5.3, bA555E18.1, C20orf88, DuEB, HARS2, pqn-68

Concentration :

0.5mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 10% glycerol, 1mM DTT

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Pasaje CF, et al. (2011) Int J Mol Med. 28(1):129-37. ;; Chowdhury A, et al. (2010) Mol Cell Biol. 30(6):1495-507.;;

Purity :

> 85% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Epigenomics (Transcription & Translation)

Molecular Weight :

25.9 kDa (232aa) confirmed by MALDI-TOF

Amino Acid Sequence :

MGSSHHHHHH SSGLVPRGSH MGSMKAVVQR VTRASVTVGG EQISAIGRGI CVLLGISLED TQKELEHMVR KILNLRVFED ESGKHWSKSV MDKQYEILCV SQFTLQCVLK GNKPDFHLAM PTEQAEGFYN SFLEQLRKTY RPELIKDGKF GAYMQVHIQN DGPVTIELES PAPGTATSDP KQLSKLEKQQ QRKEKTRAKG PSESSKERNT PRKEDRSASS GAEGDVSSER EP

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

Q8TEA8

Internal Search Terms :

DTD1, D-tyrosyl-tRNA deacylase 1, bA379J5.3, bA555E18.1, C20orf88, DuEB, HARS2, pqn-68,ATGP1831-10ug,ATGP1831-20ug,ATGP1831-50ug,ATGP1831-100ug,ATGP1831-250ug,ATGP1831-500ug,ATGP1831-1mg,ATGP1831-10,ATGP1831-20,ATGP1831-50,ATGP1831-100,ATGP1831-250,ATGP1831-500,ATGP1831-1

more info or order :

NKMAX product webpage