Recombinant human NKG2D/KLRK1 protein | NKMAX ATGP1818 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human NKG2D/KLRK1 protein

catalog :

ATGP1818

quantity :

20 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human NKG2D/KLRK1 protein

Domain :

73-216aa

Catalog number (SKU) :

ATGP1818

NCBI :

NP_031386

Description :

KLRK1 is an activating receptor that has recently generated considerable interest. The most intriguing of these are a pair of closely related proteins called MICA and MICB. These are cell-surface molecules distantly related to MHC class I proteins, and the genes possess elements of heat shock promoters. MICA and MICB, therefore, are expressed during cell stress and are up-regulated in tumor cells and during viral infections. This receptor-ligand combination may play a critical role in the immune response to a variety of pathologies. Recombinant human KLRK1 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Alternative Names :

Killer cell lectin like receptor K1, Killer cell lectin-like receptor subfamily K member 1, NKG2-D type II integral membrane protein, NK cell receptor D, NKG2-D-activating NK receptor, CD314, NKG2D, KLR, NKG2-D

Concentration :

0.5mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 0.4M urea

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Guerra N. et al. (2008) Immunity. 28:571-580.;; Ravetch JV. et al. (2000) Science. 290:84-89.;;

Purity :

> 85% by SDS-PAGE

Applications :

SDS-PAGE, Denatured

Antigen Species :

Human

Gene Category :

Immunology

Molecular Weight :

19.2 kDa (168aa)

Amino Acid Sequence :

IWSAVF LNSLFNQEVQ IPLTESYCGP CPKNWICYKN NCYQFFDESK NWYESQASCM SQNASLLKVY SKEDQDLLKL VKSYHWMGLV HIPTNGSWQW EDGSILSPNL LTIIEMQKGD CALYASSFKG YIENCSTPNT YICMQRTV

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

P26718

Internal Search Terms :

NKG2D, NKG2-D type II integral membrane protein, CD314, D12S2489E, KLR, NKG2-D, NKG2D,ATGP1818-10ug,ATGP1818-20ug,ATGP1818-50ug,ATGP1818-100ug,ATGP1818-250ug,ATGP1818-500ug,ATGP1818-1mg,ATGP1818-10,ATGP1818-20,ATGP1818-50,ATGP1818-100,ATGP1818-250,ATGP1818-500,ATGP1818-1

more info or order :

NKMAX product webpage