Recombinant human AMPK beta 2 protein | NKMAX ATGP1817 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human AMPK beta 2 protein

catalog :

ATGP1817

quantity :

20 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human AMPK beta 2 protein

Domain :

1-272aa

Catalog number (SKU) :

ATGP1817

NCBI :

NP_005390

Description :

PRKAB2 is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. PRKAB2 may be a positive regulator of AMPK activity. It is highly expressed in skeletal muscle and thus may have tissue-specific roles. Recombinant human PRKAB2 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Alternative Names :

5'-AMP-activated protein kinase subunit beta-2

Concentration :

1mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 2M urea

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Souza RP. et al. (2012) J Psychiatr Res. 46:462-468.;; Jung KC. et al. (2003) Cytogenet Genome Res. 103:202C.;;

Purity :

> 90% by SDS-PAGE

Applications :

SDS-PAGE, Denatured

Antigen Species :

Human

Gene Category :

Metabolism

Molecular Weight :

32.8 kDa (296aa)

Amino Acid Sequence :

MGNTTS DRVSGERHGA KAARSEGAGG HAPGKEHKIM VGSTDDPSVF SLPDSKLPGD KEFVSWQQDL EDSVKPTQQA RPTVIRWSEG GKEVFISGSF NNWSTKIPLI KSHNDFVAIL DLPEGEHQYK FFVDGQWVHD PSEPVVTSQL GTINNLIHVK KSDFEVFDAL KLDSMESSET SCRDLSSSPP GPYGQEMYAF RSEERFKSPP ILPPHLLQVI LNKDTNISCD PALLPEPNHV MLNHLYALSI KDSVMVLSAT HRYKKKYVTT LLYKPI

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

O43741

Internal Search Terms :

AMPK b2, 5'-AMP-activated protein kinase subunit beta-2,ATGP1817-10ug,ATGP1817-20ug,ATGP1817-50ug,ATGP1817-100ug,ATGP1817-250ug,ATGP1817-500ug,ATGP1817-1mg,ATGP1817-10,ATGP1817-20,ATGP1817-50,ATGP1817-100,ATGP1817-250,ATGP1817-500,ATGP1817-1

more info or order :

NKMAX product webpage