product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant human RCAN3 protein
catalog :
ATGP1811
quantity :
10 ug
price :
80 USD
more info or order :
NKMAX product webpage
product information
Product Type :
Proteins
Item Name :
Recombinant human RCAN3 protein
Domain :
56-241aa
Catalog number (SKU) :
ATGP1811
NCBI :
NP_038469
Description :
Calcipressin-3, also known as RCAN3, is a 241 amino acid protein that potentially is involved in central nervous system development. RCAN3 inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A. Overexpression of calcipressin-3 results in inhibition of calcineurin activity towards the nuclear factor of activated T-cells (NFAT) transcription factors and also downregulates NFAT-dependent cytokine gene expression in activated Jurkat T-cells. Highest expression occurs in heart, skeletal muscle kidney, liver and peripheral blood leukocytes. Recombinant human RCAN3 protein, fused to His-tag at N-terminus, was expressed in E. coli.
Alternative Names :
Calcipressin-3, DSCR1L2, hRCN3, MCIP3, RCN3
Concentration :
0.5mg/ml (determined by Bradford assay)
Formulation :
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 2M urea, 20% glycerol, 0.2M NaCl
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Strippoli P., et al. (2000) Genomics. 64:252-263.;; Abbasi S., et al. (2006) J Biol Chem. 281:7717-7726.;;
Purity :
> 90% by SDS-PAGE
Applications :
SDS-PAGE,Denatured
Antigen Species :
Human
Gene Category :
Neuroscience
Molecular Weight :
23.5 kDa (209aa)
Amino Acid Sequence :
MGSSHHHHHH SSGLVPRGSH MGSEAVFEAR EQKERFEALF TIYDDQVTFQ LFKSFRRVRI NFSKPEAAAR ARIELHETDF NGQKLKLYFA QVQMSGEVRD KSYLLPPQPV KQFLISPPAS PPVGWKQSED AMPVINYDLL CAVSKLGPGE KYELHAGTES TPSVVVHVCE SETEEEEETK NPKQKIAQTR RPDPPTAALN EPQTFDCAL
Tag :
His-Tag
Expression System :
E.coli
Product Type Name :
Recombinant Protein
UniProt No. :
Q9UKA8
Internal Search Terms :
RCAN3, Calcipressin-3, DSCR1L2, hRCN3, MCIP3, RCN3,ATGP1811-10ug,ATGP1811-20ug,ATGP1811-50ug,ATGP1811-100ug,ATGP1811-250ug,ATGP1811-500ug,ATGP1811-1mg,ATGP1811-10,ATGP1811-20,ATGP1811-50,ATGP1811-100,ATGP1811-250,ATGP1811-500,ATGP1811-1
more info or order :
NKMAX product webpage
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.