protein

Recombinant mouse Galectin-3/LGALS3 protein

ATGP1806

10 ug

105 USD

Recombinant mouse Galectin-3/LGALS3 protein

1-264aa

ATGP1806

NP_034835

LGALS3, also known as galectin 3, is a member of the family of animal lectins, which selectively binds beta-galactoside residues. This protein is secreted from cells by ectocytosis, which is independent of the classical secretory pathway through the endoplasmic reticulum/Golgi network. LGALS3 has been associated with the inhibition of apoptosis and the progression of cancer. It is normally distributed in epithelia of many organs, in various inflammatory cells, including macrophages, as well as dendritic cells and Kupffer cells. The expression of this lectin is up-regulated during inflammation, cell proliferation, cell differentiation and through trans-activation by viral proteins. Recombinant mouse LGALS3 protein, used to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Gal-3, 35 kDa lectin, Carbohydrate-binding protein 35, CBP 35, Galactose-specific lectin 3, IgE-binding protein, L-34 galactoside-binding lectin, Laminin-binding protein, Lectin L-29, Mac-2 antigen, MAC2

0.5mg/ml (determined by Bradford assay)

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 50% glycerol,1mM DTT, 2mM EDTA

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Barondes SH., et al. (1994) J Biol Chem. 269(33):20807-10.;; Kadrofske MM., et al. (1998) Arch Biochem Biophys. 349(1):7-20.;;

> 95% by SDS-PAGE

SDS-PAGE

Mouse

Cancer

29.8 kDa (287aa) confirmed by MALDI-TOF

MGSSHHHHHH SSGLVPRGSH MGSMADSFSL NDALAGSGNP NPQGYPGAWG NQPGAGGYPG AAYPGAYPGQ APPGAYPGQA PPGAYPGQAP PSAYPGPTAP GAYPGPTAPG AYPGSTAPGA FPGQPGAPGA YPSAPGGYPA AGPYGVPAGP LTVPYDLPLP GGVMPRMLIT IMGTVKPNAN RIVLDFRRGN DVAFHFNPRF NENNRRVIVC NTKQDNNWGK EERQSAFPFE SGKPFKIQVL VEADHFKVAV NDAHLLQYNH RMKNLREISQ LGISGDITLT SANHAMI

His-Tag

E.coli

Recombinant Protein

Q8C253

35 kDa lectin, 35kDa lectin, Carbohydrate binding protein 35, Carbohydrate-binding protein 35, CBP 35, CBP35, Gal 3, Gal3, Gal-3, galactose binding, Galactose specific lectin 3, Galactose-specific lectin 3, GALBP, Galectin 3, Galectin3, GALIG, IgE binding protein, IgE-binding protein, L34 galactoside binding lectin, L-34 galactoside binding lectin, L-34 galactoside-binding lectin, Laminin binding protein, Laminin-binding protein, Lectin, Lectin galactose binding soluble 3, Lectin L29, Lectin L-29, LGALS2, MAC 2, Mac 2 antigen, MAC2, MAC-2, Mac-2 antigen, soluble 3, ATGP1806-10ug, ATGP1806-20ug, ATGP1806-50ug, ATGP1806-100ug, ATGP1806-250ug, ATGP1806-500ug, ATGP1806-1mg, ATGP1806-010, ATGP1806-020, ATGP1806-050, ATGP1806-100, ATGP1806-250, ATGP1806-500, ATGP1806-01M