Recombinant human CLNS1A protein | NKMAX ATGP1799 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human CLNS1A protein

catalog :

ATGP1799

quantity :

20 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human CLNS1A protein

Domain :

1-237aa

Catalog number (SKU) :

ATGP1799

NCBI :

NP_001284

Description :

CLNS1A, also as known as, Methylosome subunit pICln, belongs to the pICln (TC 1. A. 47) family. CLNS1A protein has functions in multiple regulatory pathways. This protein interaction with Sm proteins inhibits their assembly on u RNA and interferes with snRNP biogenesis. It is Inhibits the binding of survival motor neuron protein (SMN) to Sm proteins. And this protein is also found associated with the plasma membrane where it functions as a chloride current regulator. Recombinant human CLNS1A protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Alternative Names :

Methylosome subunit pICln, CLCI, CLNS1B, Icln

Concentration :

1mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 10% glycerol, 2mM DTT

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Pu W.T., et al. (1999) Mol. Cell. Biol. 19:4113-4120;; Friesen W.J., et al. (2001) Mol. Cell. Biol. 21:8289-8300;;

Purity :

> 90% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Epigenomics (Transcription & Translation)

Molecular Weight :

28.7 kDa (261aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)

Amino Acid Sequence :

MGSHMSFLKS FPPPGPAEGL LRQQPDTEAV LNGKGLGTGT LYIAESRLSW LDGSGLGFSL EYPTISLHAL SRDRSDCLGE HLYVMVNAKF EEESKEPVAD EEEEDSDDDV EPITEFRFVP SDKSALEAMF TAMCECQALH PDPEDEDSDD YDGEEYDVEA HEQGQGDIPT FYTYEEGLSH LTAEGQATLE RLEGMLSQSV SSQYNMAGVR TEDSIRDYED GMEVDTTPTV AGQFEDADVD H

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

P54105

Internal Search Terms :

CLNS1A, Methylosome subunit pICln, CLCI, CLNS1B, Icln,ATGP1799-10ug,ATGP1799-20ug,ATGP1799-50ug,ATGP1799-100ug,ATGP1799-250ug,ATGP1799-500ug,ATGP1799-1mg,ATGP1799-10,ATGP1799-20,ATGP1799-50,ATGP1799-100,ATGP1799-250,ATGP1799-500,ATGP1799-1

more info or order :

NKMAX product webpage