Recombinant human UMPS protein | NKMAX ATGP1788 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human UMPS protein

catalog :

ATGP1788

quantity :

20 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human UMPS protein

Domain :

1-480aa

Catalog number (SKU) :

ATGP1788

NCBI :

NP_000364

Description :

uridine 5'-monophosphate synthase, also known as uMPS, is a bifunctional enzyme that catalyzes the final two steps of the de novo pyrimidine biosynthetic pathway. unlike prokaryotes, uMPS in eukaryotes combines the orotate phosphoribosyltransferase and the orotidine-5'-monophosphate (OMP) decarboxylase activities into a single protein. The union of these two enzymes is thought to stabilize the catalytic centers due to the low molar concentration of the protein in mammalian cells. Defects in this gene are the cause of hereditary orotic aciduria. Recombinant human uMPS protein, fused to His-tag at N-terminus, was expressed in E. coli.

Alternative Names :

uridine 5'-monophosphate synthase, OPRT

Concentration :

1mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 2M urea, 20% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Suchi M., et al. (1997) Genet. 60:525-539.;; Yablonski M J., et al. (1996) J Biol Chem. 271:10704-10708.;;

Purity :

> 90% by SDS-PAGE

Applications :

SDS-PAGE,Denatured

Antigen Species :

Human

Gene Category :

Metabolism

Molecular Weight :

54.3 kDa (500aa)

Amino Acid Sequence :

MGSSHHHHHH SSGLVPRGSH MAVARAALGP LVTGLYDVQA FKFGDFVLKS GLSSPIYIDL RGIVSRPRLL SQVADILFQT AQNAGISFDT VCGVPYTALP LATVICSTNQ IPMLIRRKET KDYGTKRLVE GTINPGETCL IIEDVVTSGS SVLETVEVLQ KEGLKVTDAI VLLDREQGGK DKLQAHGIRL HSVCTLSKML EILEQQKKVD AETVGRVKRF IQENVFVAAN HNGSPLSIKE APKELSFGAR AELPRIHPVA SKLLRLMQKK ETNLCLSADV SLARELLQLA DALGPSICML KTHVDILNDF TLDVMKELIT LAKCHEFLIF EDRKFADIGN TVKKQYEGGI FKIASWADLV NAHVVPGSGV VKGLQEVGLP LHRGCLLIAE MSSTGSLATG DYTRAAVRMA EEHSEFVVGF ISGSRVSMKP EFLHLTPGVQ LEAGGDNLGQ QYNSPQEVIG KRGSDIIIVG RGIISAADRL EAAEMYRKAA WEAYLSRLGV

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

P11172

Internal Search Terms :

UMPS, uridine 5'-monophosphate synthase, OPRT,ATGP1788-10ug,ATGP1788-20ug,ATGP1788-50ug,ATGP1788-100ug,ATGP1788-250ug,ATGP1788-500ug,ATGP1788-1mg,ATGP1788-10,ATGP1788-20,ATGP1788-50,ATGP1788-100,ATGP1788-250,ATGP1788-500,ATGP1788-1

more info or order :

NKMAX product webpage