product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant human ASGR2 protein
catalog :
ATGP1776
quantity :
20 ug
price :
80 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant human ASGR2 protein
Domain :
80-311aa
Catalog number (SKU) :
ATGP1776
NCBI :
NP_001172
Description :
ASGR2 is a subunit of the asialoglycoprotein receptor. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. It may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. ASGR2 is a hetero-oligomeric protein composed of major and minor subunits, which are encoded by different genes. ASGR2 is the less abundant minor subunit. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Recombinant human ASGR2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Alternative Names :
Asialoglycoprotein receptor 2, ASGP-R2; ASGPR2; CLEC4H2; HBXBP; HL-2
Concentration :
0.5mg/ml (determined by Bradford assay)
Formulation :
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 30% glycerol, 1mM DTT
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Seow YY., et al. (2002). Nephron. 91(3):431-8.;; Veselkin E., et al. (2011). PLoS One. 6(11):e27210.
Purity :
> 90% by SDS-PAGE
Applications :
SDS-PAGE
Antigen Species :
Human
Gene Category :
Signal Transduction
Molecular Weight :
28.9 kDa (255aa) confirmed by MALDI-TOF
Amino Acid Sequence :
MGSSHHHHHH SSGLVPRGSH MGSQSEGHRG AQLQAELRSL KEAFSNFSSS TLTEVQAIST HGGSVGDKIT SLGAKLEKQQ QDLKADHDAL LFHLKHFPVD LRFVACQMEL LHSNGSQRTC CPVNWVEHQG SCYWFSHSGK AWAEAEKYCQ LENAHLVVIN SWEEQKFIVQ HTNPFNTWIG LTDSDGSWKW VDGTDYRHNY KNWAVTQPDN WHGHELGGSE DCVEVQPDGR WNDDFCLQVY RWVCEKRRNA TGEVA
Tag :
His-Tag
Expression System :
E.coli
Product Type Name :
Recombinant Protein
UniProt No. :
P07307
Internal Search Terms :
ASGR2, Asialoglycoprotein receptor 2, ASGP-R2; ASGPR2; CLEC4H2; HBXBP; HL-2,ATGP1776-10ug,ATGP1776-20ug,ATGP1776-50ug,ATGP1776-100ug,ATGP1776-250ug,ATGP1776-500ug,ATGP1776-1mg,ATGP1776-10,ATGP1776-20,ATGP1776-50,ATGP1776-100,ATGP1776-250,ATGP1776-500,ATGP1776-1
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.