product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant human TFB2M protein
catalog :
ATGP1773
quantity :
10 ug
price :
99 USD
more info or order :
NKMAX product webpage
product information
Product Type :
Proteins
Item Name :
Recombinant human TFB2M protein
Domain :
20-396aa
Catalog number (SKU) :
ATGP1773
NCBI :
NP_071761.1
Description :
TFB2M is S-adenosyl-L-methionine-dependent methyltransferase which specifically dimethylates mitochondrial 12S rRNA at the conserved stem loop. This protein is also required for basal transcription of mitochondrial DNA, probably via its interaction with POLRMT and TFAM. TFB2M stimulates transcription independently of the methyltransferase activity. Compared to TFB1M, it activates transcription of mitochondrial DNA more efficiently, while it has less methyltransferase activity. Recombinant human TFB2M protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Alternative Names :
Dimethyladenosine transferase 2 mitochondrial, Dimethyladenosine transferase 2, mitochondrial, Hkp1, mtTFB2
Concentration :
0.5mg/ml (determined by Bradford assay)
Formulation :
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol,1mM DTT
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Litonin,D.,et al. (2010) J. Biol. Chem. 285 (24), 18129-18133;; Norrbom,J.,et al. (2010) Acta Physiol (Oxf) 198 (1), 71-79.
Purity :
> 90% by SDS-PAGE
Applications :
SDS-PAGE
Antigen Species :
Human
Gene Category :
Metabolism
Molecular Weight :
45.8 kDa (401aa) confirmed by MALDI-TOF
Amino Acid Sequence :
AGRFCI LGSEAATRKH LPARNHCGLS DSSPQLWPEP DFRNPPRKAS KASLDFKRYV TDRRLAETLA QIYLGKPSRP PHLLLECNPG PGILTQALLE AGAKVVALES DKTFIPHLES LGKNLDGKLR VIHCDFFKLD PRSGGVIKPP AMSSRGLFKN LGIEAVPWTA DIPLKVVGMF PSRGEKRALW KLAYDLYSCT SIYKFGRIEV NMFIGEKEFQ KLMADPGNPD LYHVLSVIWQ LACEIKVLHM EPWSSFDIYT RKGPLENPKR RELLDQLQQK LYLIQMIPRQ NLFTKNLTPM NYNIFFHLLK HCFGRRSATV IDHLRSLTPL DARDILMQIG KQEDEKVVNM HPQDFKTLFE TIERSKDCAY KWLYDETLED R
Tag :
His-Tag
Expression System :
E.coli
Product Type Name :
Recombinant Protein
UniProt No. :
Q9H5Q4
Internal Search Terms :
TFB2M, Dimethyladenosine transferase 2 mitochondrial, Dimethyladenosine transferase 2, mitochondrial, Hkp1, mtTFB2,ATGP1773-10ug,ATGP1773-20ug,ATGP1773-50ug,ATGP1773-100ug,ATGP1773-250ug,ATGP1773-500ug,ATGP1773-1mg,ATGP1773-10,ATGP1773-20,ATGP1773-50,ATGP1773-100,ATGP1773-250,ATGP1773-500,ATGP1773-1
more info or order :
NKMAX product webpage
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.