product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant human TSC22D3 protein
catalog :
ATGP1760
quantity :
10 ug
price :
105 USD
more info or order :
NKMAX product webpage
product information
Product Type :
Proteins
Item Name :
Recombinant human TSC22D3 protein
Domain :
1-134aa
Catalog number (SKU) :
ATGP1760
NCBI :
NP_004080
Description :
TSC22 domain family protein 3, also known as TSC22D3, protects T-cells from IL2 deprivation-induced apoptosis through the inhibition of FOXO3A transcriptional activity that leads to the down-regulation of the pro-apoptotic factor BCL2L11. In macrophages, TSC22D3 plays a role in the anti-inflammatory and immunosuppressive effects of glucocorticoids and IL10. In T-cells, TSC22D3 inhibits anti-CD3-induced NFKB1 nuclear translocation. In vitro, suppresses AP1 and NFKB1 DNA-binding activities. Recombinant human TSC22D3 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Alternative Names :
TSC22 domain family protein 3, DIP, DSIPI, GILZ, hDIP, TSC-22R
Concentration :
1mg/ml (determined by Bradford assay)
Formulation :
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Asselin-Labat M.-L., et al. (2004) Blood. 104:215-223;; Berrebi D., et al. (2003) Blood. 101:729-738
Purity :
> 85% by SDS-PAGE
Applications :
SDS-PAGE
Antigen Species :
Human
Gene Category :
Epigenomics (Transcription & Translation)
Molecular Weight :
17.2 kDa (157aa) confirmed by MALDI-TOF
Amino Acid Sequence :
MGSSHHHHHH SSGLVPRGSH MGSMNTEMYQ TPMEVAVYQL HNFSISFFSS LLGGDVVSVK LDNSASGASV VAIDNKIEQA MDLVKNHLMY AVREEVEILK EQIRELVEKN SQLERENTLL KTLASPEQLE KFQSCLSPEE PAPESPQVPE APGGSAV
Tag :
His-Tag
Expression System :
E.coli
Product Type Name :
Recombinant Protein
UniProt No. :
Q99576
Internal Search Terms :
TSC22D3, TSC22 domain family protein 3, DIP, DSIPI, GILZ, hDIP, TSC-22R,ATGP1760-10ug,ATGP1760-20ug,ATGP1760-50ug,ATGP1760-100ug,ATGP1760-250ug,ATGP1760-500ug,ATGP1760-1mg,ATGP1760-10,ATGP1760-20,ATGP1760-50,ATGP1760-100,ATGP1760-250,ATGP1760-500,ATGP1760-1
more info or order :
NKMAX product webpage
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.