Recombinant human RNA polymerase III subunit RPC8/POLR3H protein

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human RNA polymerase III subunit RPC8/POLR3H protein

catalog :

ATGP1755

quantity :

20 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human RNA polymerase III subunit RPC8/POLR3H protein

Domain :

1-204aa

Catalog number (SKU) :

ATGP1755

NCBI :

NP_612211

Description :

POLR3H, also as known as A1665 and RPC8, belongs to the eukaryotic RPB7/RPC8 RNA polymerase subunit family. POLR3H is DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. It plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. POLR3H acts as nuclear and cytosolic DNA sensor involved in innate immune response. Recombinant human POLR3H protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Alternative Names :

DNA-directed RNA polymerase III subunit RPC8, RPC22.9, RPC8

Concentration :

0.5mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 10% glycerol, 1mM DTT

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Ablasser A., et al. (2009) Nat. Immunol. 10:1065-1072;; Hu P., et al. (2002) Mol. Cell. Biol. 22:8044-8055

Purity :

> 90% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Epigenomics (Transcription & Translation)

Molecular Weight :

25.3 kDa (227aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)

Amino Acid Sequence :

MGSSHHHHHH SSGLVPRGSH MGSMFVLVEM VDTVRIPPWQ FERKLNDSIA EELNKKLANK VVYNVGLCIC LFDITKLEDA YVFPGDGASH TKVHFRCVVF HPFLDEILIG KIKGCSPEGV HVSLGFFDDI LIPPESLQQP AKFDEAEQVW VWEYETEEGA HDLYMDTGEE IRFRVVDESF VDTSPTGPSS ADATTSSEEL PKKEAPYTLV GSISEPGLGL LSWWTSN

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

Q9Y535

Internal Search Terms :

POLR3H, DNA-directed RNA polymerase III subunit RPC8, RPC22.9, RPC8,ATGP1755-10ug,ATGP1755-20ug,ATGP1755-50ug,ATGP1755-100ug,ATGP1755-250ug,ATGP1755-500ug,ATGP1755-1mg,ATGP1755-10,ATGP1755-20,ATGP1755-50,ATGP1755-100,ATGP1755-250,ATGP1755-500,ATGP1755-1

more info or order :

NKMAX product webpage