product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant human ECSIT protein
catalog :
ATGP1745
quantity :
10 ug
price :
80 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant human ECSIT protein
Domain :
19-217aa
Catalog number (SKU) :
ATGP1745
NCBI :
NP_001135937
Description :
ECSIT is a ubiquitously expressed protein that plays an important role as an adaptor protein in the cytosolic signal transduction cascade events triggered by Toll receptor activation. It was initially identified as a cytoplasmic protein interacting specifically with TNF receptor associated factor (TRAF) -6 in the TLR pathway. Knockdown of ECSIT results in severely impaired complex I assembly and disturbed mitochondrial function. Recombinant human ECSIT protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Alternative Names :
Evolutionarily conserved signaling intermediate in Toll pathway mitochondrial, Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial, SITPEC
Concentration :
1mg/ml (determined by Bradford assay)
Formulation :
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 10% glycerol,1mM DTT
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Moustakas A., et al. (2003) Genes Dev17:2855-2859;; Vogel R O., et al. (2007) Genes Dev. 21: 615-624.
Purity :
> 90% by SDS-PAGE
Applications :
SDS-PAGE
Antigen Species :
Human
Gene Category :
Immunology
Molecular Weight :
24.6 kDa (222aa) confirmed by MALDI-TOF
Amino Acid Sequence :
MGSSHHHHHH SSGLVPRGSH MGSGTCGAAL TGTSISQVPL PKDSTGAADP PQPHIVGIQS PDQQAALARH NPARPVFVEG PFSLWLRNKC VYYHILRADL LPPEEREVEE TPEEWNLYYP MQLDLEYVRS GWDNYEFDIN EVEEGPVFAM CMAGAHDQAT MAKWIQGLQE TNPTLAQIPV VFRLAGSTRE LQTSSAGLEE PPLPEDHQEE DDNLQRQQQG QS
Tag :
His-Tag
Expression System :
E.coli
Product Type Name :
Recombinant Protein
UniProt No. :
Q9BQ95
Internal Search Terms :
ECSIT, Evolutionarily conserved signaling intermediate in Toll pathway mitochondrial, Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial, SITPEC,ATGP1745-10ug,ATGP1745-20ug,ATGP1745-50ug,ATGP1745-100ug,ATGP1745-250ug,ATGP1745-500ug,ATGP1745-1mg,ATGP1745-10,ATGP1745-20,ATGP1745-50,ATGP1745-100,ATGP1745-250,ATGP1745-500,ATGP1745-1
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.