Recombinant human Kallikrein 7/KLK7 protein | NKMAX ATGP1737 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human Kallikrein 7/KLK7 protein

catalog :

ATGP1737

quantity :

20 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human Kallikrein 7/KLK7 protein

Domain :

30-253aa

Catalog number (SKU) :

ATGP1737

NCBI :

NP_005037

Description :

KLK7 is a member of the kallikrein subfamily of serine proteases. These enzymes have diverse physiological functions and many kallikreins are biomarkers for cancer. The protein has chymotrypsin-like activity and plays a role in the proteolysis of intercellular cohesive structures that precedes desquamation, the shedding of the outermost layer of the epidermis. KLK7 may play a role in cancer invasion and metastasis, and increased expression of this protein is associated with unfavorable prognosis and progression of several types of cancer. Polymorphisms in this gene may play a role in the development of atopic dermatitis. Recombinant human KLK7 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Alternative Names :

Stratum corneum chymotryptic enzyme, Serine protease 6, SCCE, PRSS6, KLK7, Kallikrein-7 isoform 2, Kallikrein-7, Kallikrein related peptidase 7, HK7

Concentration :

1mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 2M uREA, 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Talieri,M.,et al. (2011) Anticancer Res. 31 (9), 3093-3100;; Ramani,V.C., et al. (2011) Biochim. Biophys. Acta 1813 (8), 1525-1531

Purity :

> 90% by SDS-PAGE

Applications :

SDS-PAGE, Denatured

Antigen Species :

Human

Gene Category :

Cancer

Molecular Weight :

27.1 kDa (249aa)

Amino Acid Sequence :

MGSSHHHHHH SSGLVPRGSH MGSHMIIDGA PCARGSHPWQ VALLSGNQLH CGGVLVNERW VLTAAHCKMN EYTVHLGSDT LGDRRAQRIK ASKSFRHPGY STQTHVNDLM LVKLNSQARL SSMVKKVRLP SRCEPPGTTC TVSGWGTTTS PDVTFPSDLM CVDVKLISPQ DCTKVYKDLL ENSMLCAGIP DSKKNACNGD SGGPLVCRGT LQGLVSWGTF PCGQPNDPGV YTQVCKFTKW INDTMKKHR

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

P49862

Internal Search Terms :

Stratum corneum chymotryptic enzyme, Serine protease 6, SCCE, PRSS6, KLK7, Kallikrein-7 isoform 2, Kallikrein-7, Kallikrein related peptidase 7, HK7, ATGP1737-10ug, ATGP1737-20ug, ATGP1737-50ug, ATGP1737-100ug, ATGP1737-250ug, ATGP1737-500ug, ATGP1737-1mg, ATGP1737-010, ATGP1737-020, ATGP1737-050, ATGP1737-100, ATGP1737-250, ATGP1737-500, ATGP1737-01M

more info or order :

NKMAX product webpage