Recombinant human ULBP-1 protein | NKMAX ATGP1731 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human ULBP-1 protein

catalog :

ATGP1731

quantity :

20 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human ULBP-1 protein

Domain :

26-216aa

Catalog number (SKU) :

ATGP1731

NCBI :

NP_079494

Description :

uLBP1 is ligand for the NKG2D receptor, together with at least uLBP2 and uLBP3. uLBPs activate multiple signaling pathways in primary NK cells, resulting in the production of cytokines and chemokines. In CMV infected cells, uLBP1 interacts with soluble CMV glycoprotein uL16. The interaction with uL16 blocked the interaction with the NKG2D receptor, providing a mechanism by which CMV infected cells might escape the immune system. uL16 also causes uLBP1 to be retained in the ER and cis-Golgi apparatus so that it does not reach the cell surface. Recombinant human uLBP1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Alternative Names :

UL16 binding protein 1, ALCAN-beta, NKG2D ligand 1, N2DL-1, NKG2DL1, Retinoic acid early transcript 1I, RAET1I

Concentration :

0.5mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 30% glycerol, 1mM DTT

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Cerwenka A., et al. (2003). Tissue Antigens. 61:335-343.;; Bacon L., et al. (2004). J Immunol. 173:1078-1084.

Purity :

> 90% by SDS-PAGE

Applications :

SDS-PAGE, Denatured

Antigen Species :

Human

Gene Category :

Immunology

Molecular Weight :

25 kDa (216aa) confirmed by MALDI-TOF

Amino Acid Sequence :

GWVDT HCLCYDFIIT PKSRPEPQWC EVQGLVDERP FLHYDCVNHK AKAFASLGKK VNVTKTWEEQ TETLRDVVDF LKGQLLDIQV ENLIPIEPLT LQARMSCEHE AHGHGRGSWQ FLFNGQKFLL FDSNNRKWTA LHPGAKKMTE KWEKNRDVTM FFQKISLGDC KMWLEEFLMY WEQMLDPTKP PSLAPG

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

Q9BZM6

Internal Search Terms :

ULBP1, NKG2D ligand 1, uL16 binding protein 1, RAET1I, N2DL-1, N2DL1, NKG2D ligand 1,ATGP1731-10ug,ATGP1731-20ug,ATGP1731-50ug,ATGP1731-100ug,ATGP1731-250ug,ATGP1731-500ug,ATGP1731-1mg,ATGP1731-10,ATGP1731-20,ATGP1731-50,ATGP1731-100,ATGP1731-250,ATGP1731-500,ATGP1731-1

more info or order :

NKMAX product webpage