product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant human p21/CIP1/CDKN1A protein
catalog :
ATGP1725
quantity :
10 ug
price :
130 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant human p21/CIP1/CDKN1A protein
Domain :
1-164aa
Catalog number (SKU) :
ATGP1725
NCBI :
NP_000380.1
Description :
CDKN1A, also known as P21 or WAF1, plays a critical role in the cellular response to DNA damage, and its overexpression results in cell cycle arrest. In association with CDK2 complexes, it serves to inhibit kinase activity and block progression through G1/S. However, CDKN1A may also enhance assembly and activity in complexes of CDK4 or CDK6 and cyclin D. This protein may be the important intermediate by which p53/TP53 mediates its role as an inhibitor of cellular proliferation in response to DNA damage. Recombinant human CDKN1A protein, fused to His-tag at N-terminus, was expressed in E. coli.
Alternative Names :
Cyclin-dependent kinase inhibitor 1A, P21, CIP1, SDI1, WAF1, CAP20, CDKN1, MDA-6, p21CIP1
Concentration :
0.5mg/ml (determined by Bradford assay)
Formulation :
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 2M urea, 10% glycerol, 0.1M NaCl
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
EI-Deiry W S., et al. (1994) Cancer Res. 54:1169-1174.;; Harper J W., et al. (1993) Cell. 75:805-816.
Purity :
> 85% by SDS-PAGE
Applications :
SDS-PAGE, Denatured
Antigen Species :
Human
Gene Category :
Cancer
Molecular Weight :
20.2 kDa (184aa)
Amino Acid Sequence :
MSEPAGDVRQ NPCGSKACRR LFGPVDSEQL SRDCDALMAG CIQEARERWN FDFVTETPLE GDFAWERVRG LGLPKLYLPT GPRRGRDELG GGRRPGTSPA LLQGTAEEDH VDLSLSCTLV PRSGEQAEGS PGGPGDSQGR KRRQTSMTDF YHSKRRLIFS KRKP
Tag :
His-Tag
Expression System :
E.coli
Product Type Name :
Recombinant Protein
UniProt No. :
P38936
Internal Search Terms :
p21, CIP1, CDKN1A, Cyclin-dependent kinase inhibitor 1A, P21, CIP1, SDI1, WAF1, CAP20, CDKN1, MDA-6, p21CIP1,ATGP1725-10ug,ATGP1725-20ug,ATGP1725-50ug,ATGP1725-100ug,ATGP1725-250ug,ATGP1725-500ug,ATGP1725-1mg,ATGP1725-10,ATGP1725-20,ATGP1725-50,ATGP1725-100,ATGP1725-250,ATGP1725-500,ATGP1725-1
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.