product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant human CDK4 protein
catalog :
ATGP1724
quantity :
20 ug
price :
80 USD
more info or order :
NKMAX product webpage
product information
Product Type :
Proteins
Item Name :
Recombinant human CDK4 protein
Domain :
1-303aa
Catalog number (SKU) :
ATGP1724
NCBI :
NP_000066
Description :
Cyclin-dependent kinase 4, also known as CDK4, belongs to the Cyclin-dependent kinases (CDK) family. CDK are the catalytic subunits of the cyclin/cdk complexes, which phosphorylate substrates on threonine/serine residues. CDK4, in complex with D-type cyclins, is thought to regulate cell growth during the G1 phase of the cell cycle. This association with a D-type cyclin upregulates CDK4 activity, whereas binding to the CDK inhibitor p16 downregulates CDK4 activity. Recombinant human CDK4 protein, fused to His-tag at N-terminus, was expressed in E. coli.
Alternative Names :
Cyclin-dependent kinase 4, CMM3, PSK-J3
Concentration :
1mg/ml (determined by Bradford assay)
Formulation :
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Serrano M., et al. (1993) Nature.366:704-707.;; Kato J Y., et al. (1994) Mol Cell Biol. 14:2713-2721.
Purity :
> 85% by SDS-PAGE
Applications :
SDS-PAGE,Denatured
Antigen Species :
Human
Gene Category :
Cell Cycle
Molecular Weight :
36.1 kDa (326aa)
Amino Acid Sequence :
MGSSHHHHHH SSGLVPRGSH MGSMATSRYE PVAEIGVGAY GTVYKARDPH SGHFVALKSV RVPNGGGGGG GLPISTVREV ALLRRLEAFE HPNVVRLMDV CATSRTDREI KVTLVFEHVD QDLRTYLDKA PPPGLPAETI KDLMRQFLRG LDFLHANCIV HRDLKPENIL VTSGGTVKLA DFGLARIYSY QMALTPVVVT LWYRAPEVLL QSTYATPVDM WSVGCIFAEM FRRKPLFCGN SEADQLGKIF DLIGLPPEDD WPRDVSLPRG AFPPRGPRPV QSVVPEMEES GAQLLLEMLT FNPHKRISAF RALQHSYLHK DEGNPE
Tag :
His-Tag
Expression System :
E.coli
Product Type Name :
Recombinant Protein
UniProt No. :
P11802
Internal Search Terms :
CDK4, Cyclin-dependent kinase 4, CMM3, PSK-J3,ATGP1724-10ug,ATGP1724-20ug,ATGP1724-50ug,ATGP1724-100ug,ATGP1724-250ug,ATGP1724-500ug,ATGP1724-1mg,ATGP1724-10,ATGP1724-20,ATGP1724-50,ATGP1724-100,ATGP1724-250,ATGP1724-500,ATGP1724-1
more info or order :
NKMAX product webpage
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.