Recombinant human TNFRSF7/CD27 protein | NKMAX ATGP1710 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human TNFRSF7/CD27 protein

catalog :

ATGP1710

quantity :

20 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human TNFRSF7/CD27 protein

Domain :

21-191aa

Catalog number (SKU) :

ATGP1710

NCBI :

NP_001233

Description :

TNFRSF7, also known as CD27, is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. Recombinant human CD27 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Alternative Names :

CD27L receptor, T-cell activation antigen CD27, T14, Tumor necrosis factor receptor superfamily member 7, TNFRSF7, T cell antivation antigen S152, TP55

Concentration :

1mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Gravestein L.A., et al. (1998) Eur. J. Immunol. 28:2208-2216;; Prasad K.V.S., et al. (1997) Proc. Natl. Acad. Sci. u.S.A. 94:6346-6351

Purity :

> 90% by SDS-PAGE

Applications :

SDS-PAGE, Denatured

Antigen Species :

Human

Gene Category :

Cancer

Molecular Weight :

21.8 kDa (196aa)

Amino Acid Sequence :

MGSSHHHHHH SSGLVPRGSH MGSHMTPAPK SCPERHYWAQ GKLCCQMCEP GTFLVKDCDQ HRKAAQCDPC IPGVSFSPDH HTRPHCESCR HCNSGLLVRN CTITANAECA CRNGWQCRDK ECTECDPLPN PSLTARSSQA LSPHPQPTHL PYVSEMLEAR TAGHMQTLAD FRQLPARTLS THWPPQRSLC SSDFIR

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

P26842

Internal Search Terms :

CD27, CD27 antigen, S152, T14, TNFRSF7, Tp55,ATGP1710-10ug,ATGP1710-20ug,ATGP1710-50ug,ATGP1710-100ug,ATGP1710-250ug,ATGP1710-500ug,ATGP1710-1mg,ATGP1710-10,ATGP1710-20,ATGP1710-50,ATGP1710-100,ATGP1710-250,ATGP1710-500,ATGP1710-1

more info or order :

NKMAX product webpage