product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant human DKK2 protein
catalog :
ATGP1700
quantity :
4 ug
price :
80 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant human DKK2 protein
Domain :
34-259aa
Catalog number (SKU) :
ATGP1700
NCBI :
NP_055236
Description :
Dickkopf-related protein 2, also known as DKK2, belongs to the dickkopf family. DKK2 antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease. Recombinant human DKK2 protein, fused to His-tag at N-terminus, was expressed in E. coli.
Alternative Names :
Dickkopf-related protein 2, DKK-2
Concentration :
0.25mg/ml (determined by Bradford assay)
Formulation :
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Krupnik V.E., et al. (1999) Gene. 238:301-313;; Clark H.F., et al. (2003) Genome Res. 13:2265-2270
Purity :
> 90% by SDS-PAGE
Applications :
SDS-PAGE, Denatured
Antigen Species :
Human
Gene Category :
Stem cell
Molecular Weight :
27.6 kDa (250aa)
Amino Acid Sequence :
MGSSHHHHHH SSGLVPRGSH MGSMKLNSIK SSLGGETPGQ AANRSAGMYQ GLAFGGSKKG KNLGQAYPCS SDKECEVGRY CHSPHQGSSA CMVCRRKKKR CHRDGMCCPS TRCNNGICIP VTESILTPHI PALDGTRHRD RNHGHYSNHD LGWQNLGRPH TKMSHIKGHE GDPCLRSSDC IEGFCCARHF WTKICKPVLH QGEVCTKQRK KGSHGLEIFQ RCDCAKGLSC KVWKDATYSS KARLHVCQKI
Tag :
His-Tag
Expression System :
E.coli
Product Type Name :
Recombinant Protein
UniProt No. :
Q9UBU2
Internal Search Terms :
Dickkopf related protein 2, Dickkopf-related protein 2, DKK-2, DKK 2, DKK2, ATGP1700-10ug, ATGP1700-20ug, ATGP1700-50ug, ATGP1700-100ug, ATGP1700-250ug, ATGP1700-500ug, ATGP1700-1mg, ATGP1700-010, ATGP1700-020, ATGP1700-050, ATGP1700-100, ATGP1700-250, ATGP1700-500, ATGP1700-01M
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.