product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant human MCL1 protein
catalog :
ATGP1696
quantity :
10 ug
price :
105 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant human MCL1 protein
Domain :
1-327aa
Catalog number (SKU) :
ATGP1696
NCBI :
NP_068779
Description :
MCL1, also known as BCL2L3, belongs to the Bcl-2 family. MCL1 is involved in the regulation of apoptosis versus cell survival, and in the maintenance of viability but not of proliferation. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified. The longer gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene product (isoform 2) promotes apoptosis and is death-inducing. Recombinant human MCL1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques
Alternative Names :
induced myeloid leukemia cell differentiation protein Mcl-1, BCL2L3, mcl1/EAT, myeloid cell leukemia sequence 1, Bcl-2-like protein 3
Concentration :
0.25mg/ml (determined by Bradford assay)
Formulation :
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 20% glycerol, 2mM DTT
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Bingle C.D., et al. (2000) J. Biol. Chem. 275:22136-22146;; Bae J., et al. (2000) J. Biol. Chem. 275:25255-25261
Purity :
> 90% by SDS-PAGE
Applications :
SDS-PAGE
Antigen Species :
Human
Gene Category :
Metabolism
Molecular Weight :
37.2 kDa (347aa) confirmed by MALDI-TOF
Amino Acid Sequence :
MFGLKRNAVI GLNLYCGGAG LGAGSGGATR PGGRLLATEK EASARREIGG GEAGAVIGGS AGASPPSTLT PDSRRVARPP PIGAEVPDVT ATPARLLFFA PTRRAAPLEE MEAPAADAIM SPEEELDGYE PEPLGKRPAV LPLLELVGES GNNTSTDGSL PSTPPPAEEE EDELYRQSLE IISRYLREQA TGAKDTKPMG RSGATSRKAL ETLRRVGDGV QRNHETAFQG MLRKLDIKNE DDVKSLSRVM IHVFSDGVTN WGRIVTLISF GAFVAKHLKT INQESCIEPL AESITDVLVR TKRDWLVKQR GWDGFVEFFH VEDLEGG
Tag :
His-Tag
Expression System :
E.coli
Product Type Name :
Recombinant Protein
UniProt No. :
Q07820
Internal Search Terms :
MCL1,ATGP1696-10ug,ATGP1696-20ug,ATGP1696-50ug,ATGP1696-100ug,ATGP1696-250ug,ATGP1696-500ug,ATGP1696-1mg,ATGP1696-10,ATGP1696-20,ATGP1696-50,ATGP1696-100,ATGP1696-250,ATGP1696-500,ATGP1696-1
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.