Recombinant human TBCC protein | NKMAX ATGP1673 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human TBCC protein

catalog :

ATGP1673

quantity :

10 ug

price :

130 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human TBCC protein

Domain :

1-346aa

Catalog number (SKU) :

ATGP1673

NCBI :

NP_003183

Description :

TBCC (tubulin folding cofactor C) belongs to the TBCC family. It is plays a role in the regulation of centrosome and Golgi apparatus positioning, with consequences on cell shape and cell migration. Cofactor C is one of four proteins (cofactors A, D, E and C) involved in the pathway leading to correctly folded b-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing b-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/b-tubulin complex; interaction with cofactor C then causes the release of b-tubulin polypeptides. Recombinant human TBCC protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Alternative Names :

Tubulin-specific chaperone C, CFC, tubulin folding cofactor C

Concentration :

0.5mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 10% glycerol,1mM DTT

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Goncalves J., et al. (2010) EMBO Rep. 11:194-200;; Lewis SA, et al. (1996). J. Cell Biol. 132 (1-2): 1-4.

Purity :

> 85% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Cytoskeleton

Molecular Weight :

41.7 kDa (369aa) confirmed by MALDI-TOF

Amino Acid Sequence :

MESVSCS AAAVRTGDME SQRDLSLVPE RLQRREQERQ LEVERRKQKR QNQEVEKENS HFFVATFARE RAAVEELLER AESVERLEEA ASRLQGLQKL INDSVFFLAA YDLRQGQEAL ARLQAALAER RRGLQPKKRF AFKTRGKDAA SSTKVDAAPG IPPAVESIQD SPLPKKAEGD LGPSWVCGFS NLESQVLEKR ASELHQRDVL LTELSNCTVR LYGNPNTLRL TKAHSCKLLC GPVSTSVFLE DCSDCVLAVA CQQLRIHSTK DTRIFLQVTS RAIVEDCSGI QFAPYTWSYP EIDKDFESSG LDRSKNNWND VDDFNWLARD MASPNWSILP EEERNIQWD

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

Q15814

Internal Search Terms :

TBCC, Tubulin-specific chaperone C, CFC, tubulin folding cofactor C,ATGP1673-10ug,ATGP1673-20ug,ATGP1673-50ug,ATGP1673-100ug,ATGP1673-250ug,ATGP1673-500ug,ATGP1673-1mg,ATGP1673-10,ATGP1673-20,ATGP1673-50,ATGP1673-100,ATGP1673-250,ATGP1673-500,ATGP1673-1

more info or order :

NKMAX product webpage