Recombinant human DKK3 protein | NKMAX ATGP1666 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human DKK3 protein

catalog :

ATGP1666

quantity :

20 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human DKK3 protein

Domain :

22-350aa

Catalog number (SKU) :

ATGP1666

NCBI :

NP_001018067

Description :

Dickkopf-related protein 3, also known as DKK3, is a member of the DKK protein family including Dkk-1, 2, 3 and -4. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. DKK3 is a 350 amino acid secreted glycoprotein that is composed of an N-terminal signal peptide and two conserved cysteine-rich domains, which are separated by a 12 amino acid linker region. The expression of this gene is decreased in a variety of cancer cell lines and it may function as a tumor suppressor gene. Recombinant human DKK3 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Alternative Names :

Dickkopf WNT signaling pathway inhibitor 3, Dickkopf-related protein 3, Dickkopf-3, Dkk-3, REIC, RIG, CRRL

Concentration :

0.5mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 1M urea,10% glycerol, 1mM DTT

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Cadigan K M., et al. (1997) Genes Dev. 11:3286-3305.;; Gilnka A., et al. (1998) Nature. 391:357-362.

Purity :

> 85% by SDS-PAGE

Applications :

SDS-PAGE, Denatured

Antigen Species :

Human

Gene Category :

Signal Transduction

Molecular Weight :

38.8 kDa (353aa)

Amino Acid Sequence :

MGSSHHHYHH SSGLVPRGSH MGSMAPAPTA TSAPVKPGPA LSYPQEEATL NEMFREVEEL MEDTQHKLRS AVEEMEAEEA AAKASSEVNL ANLPPSYHNE TNTDTKVGNN TIHVHREIHK ITNNQTGQMV FSETVITSVG DEEGRRSHEC IIDEDCGPSM YCQFASFQYT CQPCRGQRML CTRDSECCGD QLCVWGHCTK MATRGSNGTI CDNQRDCQPG LCCAFQRGLL FPVCTPLPVE GELCHDPASR LLDLITWELE PDGALDRCPC ASGLLCQPHS HSLVYVCKPT FVGSRDQDGE ILLPREVPDE YEVGSFMEEV RQELEDLERS LTEEMALREP AAAAAALLGG EEI

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

Q9UBP4

Internal Search Terms :

Cardiomyocyte regeneration-related lncRNA, CRRL, Dickkopf, Dickkopf 3 homolog, Dickkopf WNT signaling pathway inhibitor 3, Dickkopf-3, Dickkopf-related protein 3, Dickkopf-related protein 3 precursor, DKK3, Dkk-3, Regulated in glioma, REIC, RIG, Xenopus laevis, Xenopus laevis homolog 3, ATGP1666-10ug, ATGP1666-20ug, ATGP1666-50ug, ATGP1666-100ug, ATGP1666-250ug, ATGP1666-500ug, ATGP1666-1mg, ATGP1666-010, ATGP1666-020, ATGP1666-050, ATGP1666-100, ATGP1666-250, ATGP1666-500, ATGP1666-01M

more info or order :

NKMAX product webpage