Recombinant human RGS14 protein | NKMAX ATGP1625 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human RGS14 protein

catalog :

ATGP1625

quantity :

10 ug

price :

130 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human RGS14 protein

Domain :

1-566aa

Catalog number (SKU) :

ATGP1625

NCBI :

NP_006471

Description :

RGS14 (Regulator of G-protein signaling 14) belongs to regulator of G protein signalling family. This protein contains one RGS domain, two Raf-like Ras-binding domains (RBDs), and one GoLoco motif. RGS14 is highly enriched in CA2 pyramidal neurons and plays a role in suppression of both synaptic plasticity at these synapses and hippocampal-based learning and memory. RGS14 is a scaffolding protein that integrates G protein and H-Ras/ERK/MAP kinase signaling pathways, thereby making it well positioned to suppress plasticity in CA2 neurons. Recombinant human RGS14 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Alternative Names :

regulator of G-protein signaling 14

Concentration :

0.5mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 7.5) containing 10% glycerol, 1mM DTT, 200mM NaCl

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Lee SE, et al. (2010) Proc Natl Acad Sci u S A. 107(39):16994-8.;; Martin-McCaffrey L., et al. (2005) Cell Cycle 4:953-960

Purity :

> 80% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Signal Transduction

Molecular Weight :

63.6 kDa (586aa)

Amino Acid Sequence :

MPGKPKHLGV PNGRMVLAVS DGELSSTTGP QGQGEGRGSS LSIHSLPSGP SSPFPTEEQP VASWALSFER LLQDPLGLAY FTEFLKKEFS AENVTFWKAC ERFQQIPASD TQQLAQEARN IYQEFLSSQA LSPVNIDRQA WLGEEVLAEP RPDMFRAQQL QIFNLMKFDS YARFVKSPLY RECLLAEAEG RPLREPGSSR LGSPDATRKK PKLKPGKSLP LGVEELGQLP PVEGPGGRPL RKSFRRELGG TANAALRRES QGSLNSSASL DLGFLAFVSS KSESHRKSLG STEGESESRP GKYCCVYLPD GTASLALARP GLTIRDMLAG ICEKRGLSLP DIKVYLVGNE QALVLDQDCT VLADQEVRLE NRITFELELT ALERVVRISA KPTKRLQEAL QPILEKHGLS PLEVVLHRPG EKQPLDLGKL VSSVAAQRLV LDTLPGVKIS KARDKSPCRS QGCPPRTQDK ATHPPPASPS SLVKVPSSAT GKRQTCDIEG LVELLNRVQS SGAHDQRGLL RKEDLVLPEF LQLPAQGPSS EETPPQTKSA AQPIGGSLNS TTDSAL

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

O43566

Internal Search Terms :

RGS14, regulator of G-protein signaling 14,ATGP1625-10ug,ATGP1625-20ug,ATGP1625-50ug,ATGP1625-100ug,ATGP1625-250ug,ATGP1625-500ug,ATGP1625-1mg,ATGP1625-10,ATGP1625-20,ATGP1625-50,ATGP1625-100,ATGP1625-250,ATGP1625-500,ATGP1625-1

more info or order :

NKMAX product webpage