Recombinant human CD16a/FCGR3A protein | NKMAX ATGP1623 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human CD16a/FCGR3A protein

catalog :

ATGP1623

quantity :

20 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human CD16a/FCGR3A protein

Domain :

18-208aa

Catalog number (SKU) :

ATGP1623

NCBI :

NP_001121065

Description :

Low affinity immunoglobulin gamma Fc region receptor III-A (FCGR3A), also known as CD16A. This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other antibody-dependent responses. FCGR3A requires association of the gamma subunit of Fc epsilon RI or the zeta subunit of the TCR-CD3 complex for cell surface expression. Mutations in this gene have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Recombinant human FCGR3A protein, fused to His-tag at N-terminus, was expressed in E. coli.

Alternative Names :

Low affinity immunoglobulin gamma Fc region receptor III-A,low affinity immunoglobulin gamma Fc region receptor III-A isoform c, IgG Fc receptor III-A, CD16-II, CD16a antigen, Fc-gamma RIII-alpha, Fc-gamma RIII, Fc-gamma RIIIa, FcRIII, FcRIIIa, FcgammaRIIIA, FcR-10, IgG Fc receptor III-2, CD16a, FCGR3A, CD16A, FCG3, FCGR3, FCGRIII, IGFR3, IMD20, CD16

Concentration :

1mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 1M urea, 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Huizinga T W., et al. (1988) Nature. 333:667-669.;; Nagarajan S., et al. (1995) J Biol Chem. 270:25762-25770.

Purity :

> 90% by SDS-PAGE

Applications :

SDS-PAGE, Denatured

Antigen Species :

Human

Gene Category :

Immunology

Molecular Weight :

26 kDa (228aa)

Amino Acid Sequence :

MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSHMRT EDLPKAVVFL EPQWYRVLEK DSVTLKCQGA YSPEDNSTQW FHNESLISSQ ASSYFIDAAT VDDSGEYRCQ TNLSTLSDPV QLEVHIGWLL LQAPRWVFKE EDPIHLRCHS WKNTALHKVT YLQNGKGRKY FHHNSDFYIP KATLKDSGSY FCRGLFGSKN VSSETVNITI TQGLAVSTIS SFFPPGYQ

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

P08637

Internal Search Terms :

Fc g RIIIA, CD16a, Low affinity immunoglobulin gamma Fc region receptor III-A, CD16, CD16A, FCG3, FCGR3, FCGRIII, FCR-10, FCRIII, FCRIIIA, IGFR3,ATGP1623-10ug,ATGP1623-20ug,ATGP1623-50ug,ATGP1623-100ug,ATGP1623-250ug,ATGP1623-500ug,ATGP1623-1mg,ATGP1623-10,ATGP1623-20,ATGP1623-50,ATGP1623-100,ATGP1623-250,ATGP1623-500,ATGP1623-1

more info or order :

NKMAX product webpage