product summary
Loading...
company name :
NKMAX
product type :
protein
product name :
Recombinant human Thymidine Kinase 1 protein
catalog :
ATGP1610
quantity :
20 ug
price :
80 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant human Thymidine Kinase 1 protein
Domain :
1-234aa
Catalog number (SKU) :
ATGP1610
NCBI :
NP_003249.3
Description :
TK1, also known as thymidine kinase, is an enzyme, a phosphotransferase (a kinase) : 2'-deoxythymidine kinase, ATP-thymidine 5'-phosphotransferase. It is present in two forms in mammalian cells, TK1 and TK2. Thymidine kinases have a key function in the synthesis of DNA and thereby in cell division, as they are part of the unique reaction chain to introduce deoxythymidine into the DNA. Deoxythymidine is present in the body fluids as a result of degradation of DNA from food and from dead cells. Thymidine kinase is required for the action of many antiviral drugs. It is used to select hybridoma cell lines in production of monoclonal antibodies. In clinical chemistry it is used as a proliferation marker in the diagnosis, control of treatment and follow-up of malignant disease, mainly of hematological malignancies. Recombinant human TK1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.
Alternative Names :
Thymidine kinase cytosolic, Thymidine kinase, cytosolic, TK2
Concentration :
1mg/ml (determined by Bradford assay)
Formulation :
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 0.1M NaCl, 1mM DTT
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Chang Z.F., et al. (1998) J. Biol. Chem. 273:12095-12100;; Kreidberg J.A., et al. (1986) Mol. Cell. Biol. 6:2903-2909
Purity :
> 90% by SDS-PAGE
Applications :
SDS-PAGE
Antigen Species :
Human
Gene Category :
Epigenomics (Transcription & Translation)
Molecular Weight :
28 kDa (258aa) confirmed by MALDI-TOF
Amino Acid Sequence :
MSCINL PTVLPGSPSK TRGQIQVILG PMFSGKSTEL MRRVRRFQIA QYKCLVIKYA KDTRYSSSFC THDRNTMEAL PACLLRDVAQ EALGVAVIGI DEGQFFPDIV EFCEAMANAG KTVIVAALDG TFQRKPFGAI LNLVPLAESV VKLTAVCMEC FREAAYTKRL GTEKEVEVIG GADKYHSVCR LCYFKKASGQ PAGPDNKENC PVPGKPGEAV AARKLFAPQQ ILQCSPAN
Tag :
His-Tag
Expression System :
E.coli
Product Type Name :
Recombinant Protein
UniProt No. :
P04183
Internal Search Terms :
Thymidine Kinase1,ATGP1610-10ug,ATGP1610-20ug,ATGP1610-50ug,ATGP1610-100ug,ATGP1610-250ug,ATGP1610-500ug,ATGP1610-1mg,ATGP1610-10,ATGP1610-20,ATGP1610-50,ATGP1610-100,ATGP1610-250,ATGP1610-500,ATGP1610-1
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.