product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant human Ubc12/UBE2M protein
catalog :
ATGP1603
quantity :
20 ug
price :
80 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant human Ubc12/UBE2M protein
Domain :
1-183aa
Catalog number (SKU) :
ATGP1603
NCBI :
NP_003960
Description :
uBE2M, also known as NEDD8-conjugating enzyme ubc12, belongs to the ubiquitin-conjugating enzyme family. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein is linked with a ubiquitin-like protein, NEDD8, which can be conjugated to cellular proteins, such as Cdc53/culin. Recombinant human uBE2M protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.
Alternative Names :
NEDD8-conjugating enzyme Ubc12, NEDD8 carrier protein, Ubiquitin-conjugating enzyme E2 M, Homologous to yeast UBC12, Ubiquitin-conjugating enzyme E2M (UBC12 homolog, yeast), hUbc12, UBC12
Concentration :
1mg/ml (determined by Bradford assay)
Formulation :
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 0.2M NaCl, 1mM DTT
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Gong L., et al. (1999) J. Biol. Chem. 274:12036-12042;; Huang D.T., et al. (2004) Nat. Struct. Mol. Biol. 11:927-935
Purity :
> 95% by SDS-PAGE
Applications :
SDS-PAGE
Antigen Species :
Human
Gene Category :
Ubiquitination
Molecular Weight :
23.5 kDa (207aa) confirmed by MALDI-TOF
Amino Acid Sequence :
MGSSHHHHHH SSGLVPRGSH MGSHMIKLFS LKQQKKEEES AGGTKGSSKK ASAAQLRIQK DINELNLPKT CDISFSDPDD LLNFKLVICP DEGFYKSGKF VFSFKVGQGY PHDPPKVKCE TMVYHPNIDL EGNVCLNILR EDWKPVLTIN SIIYGLQYLF LEPNPEDPLN KEAAEVLQNN RRLFEQNVQR SMRGGYIGST YFERCLK
Tag :
His-Tag
Expression System :
E.coli
Product Type Name :
Recombinant Protein
UniProt No. :
P61081
Internal Search Terms :
UBE2M, Ubc12, NEDD8-conjugating enzyme ubc12, hubc12, uBC-RS2, uBC12,ATGP1603-10ug,ATGP1603-20ug,ATGP1603-50ug,ATGP1603-100ug,ATGP1603-250ug,ATGP1603-500ug,ATGP1603-1mg,ATGP1603-10,ATGP1603-20,ATGP1603-50,ATGP1603-100,ATGP1603-250,ATGP1603-500,ATGP1603-1
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.