product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant human DSTN protein
catalog :
ATGP1596
quantity :
20 ug
price :
80 USD
more info or order :
NKMAX product webpage
product information
Product Type :
Proteins
Item Name :
Recombinant human DSTN protein
Domain :
1-165aa
Catalog number (SKU) :
ATGP1596
NCBI :
NP_006861
Description :
Destrin (actin depolymerizing factor), also known as DSTN, is a member of the ADF/Cofilin/destrin superfamily that has the ability to rapidly depolymerize F-Actin in a stoichiometric manner. DSTN is a small phosphoinositide-sensitive actin-binding protein capable of depolymerizing actin-filaments in vitro. It is found in various epithelial and endothelial cells but is practically absent from adult mouse heart and skeletal muscle cells. DSTN shares 71% sequence homology with Cofilin, however the two proteins differ in their interaction with Actin. Recombinant human DSTN protein, fused to His-tag at C-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Alternative Names :
Destrin (actin depolymerizing factor), ACTDP, ADF, bA462D18.2
Concentration :
0.5mg/ml (determined by Bradford assay)
Formulation :
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 10% glycerol,1mM DTT
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Nishida E., et al. (1985) Biochemistry. 24:6624-6630.;; Kanamori T., et al. (1995) J Biol Chem. 270: 8061-8067.
Purity :
> 95% by SDS-PAGE
Applications :
SDS-PAGE
Antigen Species :
Human
Gene Category :
Actin & Myosin Related
Molecular Weight :
19.5 kDa (173aa) confirmed by MALDI-TOF
Amino Acid Sequence :
MASGVQVADE VCRIFYDMKV RKCSTPEEIK KRKKAVIFCL SADKKCIIVE EGKEILVGDV GVTITDPFKH FVGMLPEKDC RYALYDASFE TKESRKEELM FFLWAPELAP LKSKMIYASS KDAIKKKFQG IKHECQANGP EDLNRACIAE KLGGSLIVAF EGCPVLEHHH HHH
Tag :
His-Tag
Expression System :
E.coli
Product Type Name :
Recombinant Protein
UniProt No. :
P60981
Internal Search Terms :
DSTN, Destrin (actin depolymerizing factor), ACTDP, ADF, bA462D18.2,ATGP1596-10ug,ATGP1596-20ug,ATGP1596-50ug,ATGP1596-100ug,ATGP1596-250ug,ATGP1596-500ug,ATGP1596-1mg,ATGP1596-10,ATGP1596-20,ATGP1596-50,ATGP1596-100,ATGP1596-250,ATGP1596-500,ATGP1596-1
more info or order :
NKMAX product webpage
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.