Recombinant human VPS22/SNF8 protein | NKMAX ATGP1594 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human VPS22/SNF8 protein

catalog :

ATGP1594

quantity :

20 ug

price :

105 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human VPS22/SNF8 protein

Domain :

1-258aa

Catalog number (SKU) :

ATGP1594

NCBI :

NP_009172.2

Description :

SNF 8, also known as EAP30 (ELL-associated protein of 30 kDa), is localizes to both the nucleus and the cytoplasm and is a member of the SNF8 family of vacuolar sorting proteins. This protein is subunit of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. The MVB pathway mediates delivery of transmembrane proteins into the lumen of the lysosome for degradation. The ESCRT-II complex may also play a role in transcription regulation by participating in derepression of transcription by RNA polymerase II, possibly via its interaction with ELL. Recombinant human SNF8 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Alternative Names :

SNF8 subunit of ESCRT-II, Vacuolar-sorting protein SNF8, ELL-associated protein of 30 kDa, EAP30, ESCRT-II complex subunit VPS22, hVps22, VPS22, Dot3

Concentration :

0.25mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 50% glycerol, 2mM DTT, 200mM NaCl

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Maleroed L., et al. (2007) Traffic 8:1617-1629;; Raiborg C., et al. (2008) Exp. Cell Res. 314:801-813

Purity :

> 90% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Epigenomics (Transcription & Translation)

Molecular Weight :

31.4 kDa (282aa) confirmed by MALDI-TOF

Amino Acid Sequence :

HRRGV GAGAIAKKKL AEAKYKERGT VLAEDQLAQM SKQLDMFKTN LEEFASKHKQ EIRKNPEFRV QFQDMCATIG VDPLASGKGF WSEMLGVGDF YYELGVQIIE VCLALKHRNG GLITLEELHQ QVLKGRGKFA QDVSQDDLIR AIKKLKALGT GFGIIPVGGT YLIQSVPAEL NMDHTVVLQL AEKNGYVTVS EIKASLKWET ERARQVLEHL LKEGLAWLDL QAPGEAHYWL PALFTDLYSQ EITAEEAREA LP

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

Q96H20

Internal Search Terms :

SNF8, Vacuolar-sorting protein SNF8, Dot3, EAP30, VPS22,ATGP1594-10ug,ATGP1594-20ug,ATGP1594-50ug,ATGP1594-100ug,ATGP1594-250ug,ATGP1594-500ug,ATGP1594-1mg,ATGP1594-10,ATGP1594-20,ATGP1594-50,ATGP1594-100,ATGP1594-250,ATGP1594-500,ATGP1594-1

more info or order :

NKMAX product webpage