product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant human MYL12B protein
catalog :
ATGP1577
quantity :
20 ug
price :
80 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant human MYL12B protein
Domain :
1-172aa
Catalog number (SKU) :
ATGP1577
NCBI :
NP_001138417
Description :
Myosin, light chain 12B, regulatory, also known as MYL12B, is a hexameric ATPase cellular motor protein. Myosin is composed of two heavy chains, two nonphosphorylatable alkali light chains, and two phosphorylatable regulatory light chains. MYL12B regulates contraction in smooth muscle and non-muscle cells via phosphorylation by myosin light chain kinase (MLCK). Phosphorylation of myosin regulatory light chains, catalyzed by MLCK in the presence of calcium and calmodulin, increases Actin-activated myosin ATPase activity, thereby regulating contractile activity. Recombinant human MYL12B protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Alternative Names :
Myosin light chain 12B regulatory, Myosin, light chain 12B regulatory, MLC-B, MRLC2
Concentration :
1mg/ml (determined by Bradford assay)
Formulation :
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 40% glycerol, 2mM DTT
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Kumar C C., et al. (1989) Biochemistry. 28:4027-4035.;; Kolodney M S., et al. (1999) J Physiol. 515: 87-92.
Purity :
> 90% by SDS-PAGE
Applications :
SDS-PAGE
Antigen Species :
Human
Gene Category :
Actin & Myosin Related
Molecular Weight :
22.3 kDa (196aa) confirmed by MALDI-TOF
Amino Acid Sequence :
MSSKKA KTKTTKKRPQ RATSNVFAMF DQSQIQEFKE AFNMIDQNRD GFIDKEDLHD MLASLGKNPT DAYLDAMMNE APGPINFTMF LTMFGEKLNG TDPEDVIRNA FACFDEEATG TIQEDYLREL LTTMGDRFTD EEVDELYREA PIDKKGNFNY IEFTRILKHG AKDKDD
Tag :
His-Tag
Expression System :
E.coli
Product Type Name :
Recombinant Protein
UniProt No. :
O14950
Internal Search Terms :
MYL12B, Myosin light chain 12B regulatory, Myosin, light chain 12B regulatory, MLC-B, MRLC2,ATGP1577-10ug,ATGP1577-20ug,ATGP1577-50ug,ATGP1577-100ug,ATGP1577-250ug,ATGP1577-500ug,ATGP1577-1mg,ATGP1577-10,ATGP1577-20,ATGP1577-50,ATGP1577-100,ATGP1577-250,ATGP1577-500,ATGP1577-1
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.