Recombinant human NPM1 protein | NKMAX ATGP1576 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human NPM1 protein

catalog :

ATGP1576

quantity :

20 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human NPM1 protein

Domain :

1-294aa

Catalog number (SKU) :

ATGP1576

NCBI :

NP_002511.1

Description :

NPM1 is a phosphoprotein which moves between the nucleus and the cytoplasm. It is thought to be involved in several processes including regulation of the ARF/p53 pathway. A number of genes are fusion partners have been characterized, in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in NPM1 are associated with acute myeloid leukemia. Recombinant human NPM1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Alternative Names :

Nucleophosmin, B23, NPM

Concentration :

0.5mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol 0.15M NaCl,1mM DTT

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Sagawa,F., et al. (2011) EMBO J. 30 (19), 3994-4005.;; Neubauer,A., et al. (2011) Exp. Hematol. 39 (10), 1030-1042.

Purity :

> 85% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Epigenomics (Transcription & Translation)

Molecular Weight :

34.7 kDa (314aa) confirmed by MALDI-TOF

Amino Acid Sequence :

MEDSMDMDMS PLRPQNYLFG CELKADKDYH FKVDNDENEH QLSLRTVSLG AGAKDELHIV EAEAMNYEGS PIKVTLATLK MSVQPTVSLG GFEITPPVVL RLKCGSGPVH ISGQHLVAVE EDAESEDEEE EDVKLLSISG KRSAPGGGSK VPQKKVKLAA DEDDDDDDEE DDDEDDDDDD FDDEEAEEKA PVKKSIRDTP AKNAQKSNQN GKDSKPSSTP RSKGQESFKK QEKTPKTPKG PSSVEDIKAK MQASIEKGGS LPKVEAKFIN YVKNCFRMTD QEAIQDLWQW RKSL

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

P06748

Internal Search Terms :

NPM1,ATGP1576-10ug,ATGP1576-20ug,ATGP1576-50ug,ATGP1576-100ug,ATGP1576-250ug,ATGP1576-500ug,ATGP1576-1mg,ATGP1576-10,ATGP1576-20,ATGP1576-50,ATGP1576-100,ATGP1576-250,ATGP1576-500,ATGP1576-1

References with this Product :

Nakatomi K,et al. TLR4/MD-2 is a receptor for extracellular nucleophosmin 1. (Biomed Rep. 2021){https://pubmed.ncbi.nlm.nih.gov/33335727/}

more info or order :

NKMAX product webpage