product summary
Loading...
company name :
NKMAX
product type :
protein
product name :
Recombinant human MMACHC protein
catalog :
ATGP1574
quantity :
20 ug
price :
80 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant human MMACHC protein
Domain :
1-282aa
Catalog number (SKU) :
ATGP1574
NCBI :
NP_056321
Description :
The exact function of MMACHC is not known, however, its C-terminal region shows similarity to TonB, a bacterial protein involved in energy transduction for cobalamin (vitamin B12) uptake. Hence, it is postulated that this protein may have a role in the binding and intracellular trafficking of cobalamin. Mutations in this protein are associated with methylmalonic aciduria and homocystinuria type cblC. Recombinant human MMACHC protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Alternative Names :
Methylmalonic aciduria and homocystinuria type C protein, RP11-291L19.3, cblC
Concentration :
0.5mg/ml (determined by Bradford assay)
Formulation :
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Lerner-Ellis JP.,et al. (2006) Nat Genet. 38(1):93-100.;; Tsai AC.,et al. (2007) Am. J. Med. Genet. A 143A (20): 2430-4.
Purity :
> 90% by SDS-PAGE
Applications :
SDS-PAGE
Antigen Species :
Human
Gene Category :
Signal Transduction
Molecular Weight :
34.3 kDa (306aa) confirmed by MALDI-TOF
Amino Acid Sequence :
MEPKVA ELKQKIEDTL CPFGFEVYPF QVAWYNELLP PAFHLPLPGP TLAFLVLSTP AMFDRALKPF LQSCHLRMLT DPVDQCVAYH LGRVRESLPE LQIEIIADYE VHPNRRPKIL AQTAAHVAGA AYYYQRQDVE ADPWGNQRIS GVCIHPRFGG WFAIRGVVLL PGIEVPDLPP RKPHDCVPTR ADRIALLEGF NFHWRDWTYR DAVTPQERYS EEQKAYFSTP PAQRLALLGL AQPSEKPSSP SPDLPFTTPA PKKPGNPSRA RSWLSPRVSP PASPGP
Tag :
His-Tag
Expression System :
E.coli
Product Type Name :
Recombinant Protein
UniProt No. :
Q9Y4U1
Internal Search Terms :
MMACHC, Methylmalonic aciduria and homocystinuria type C protein, RP11-291L19.3, cblC,ATGP1574-10ug,ATGP1574-20ug,ATGP1574-50ug,ATGP1574-100ug,ATGP1574-250ug,ATGP1574-500ug,ATGP1574-1mg,ATGP1574-10,ATGP1574-20,ATGP1574-50,ATGP1574-100,ATGP1574-250,ATGP1574-500,ATGP1574-1
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.