Recombinant human Kallikrein 3/PSA protein | NKMAX ATGP1566 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human Kallikrein 3/PSA protein

catalog :

ATGP1566

quantity :

20 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human Kallikrein 3/PSA protein

Domain :

25-261aa

Catalog number (SKU) :

ATGP1566

NCBI :

NP_001639.1

Description :

Prostate-specific antigen (PSA), also known as gamma-seminoprotein or kallikrein-3 (KLK3), is a member of the kallikrein-related peptidase family. Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This protein is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19 and is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Recombinant human KLK3 protein, fused to His-tag at N-terminus, was expressed in E. coli.

Alternative Names :

KLK3, Prostate-specific antigen, PSA, Gamma-seminoprotein, Seminin, Kallikrein-3, P-30 antigen, Semenogelase, APS, hK3, KLK2A1, Kallikrein related peptidase 3, Prostate-specific antigen isoform 1

Concentration :

1mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.4M Urea, 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Yang Q.F., et al. (2000) J. Hum. Genet. 45:363-366;; Cramer S.D., et al. (2003) J. Natl. Cancer Inst. 95:1044-1053

Purity :

> 85% by SDS-PAGE

Applications :

SDS-PAGE, Denatured

Antigen Species :

Human

Gene Category :

Cancer

Molecular Weight :

28.8 kDa (262aa)

Amino Acid Sequence :

IVGGW ECEKHSQPWQ VLVASRGRAV CGGVLVHPQW VLTAAHCIRN KSVILLGRHS LFHPEDTGQV FQVSHSFPHP LYDMSLLKNR FLRPGDDSSH DLMLLRLSEP AELTDAVKVM DLPTQEPALG TTCYASGWGS IEPEEFLTPK KLQCVDLHVI SNDVCAQVHP QKVTKFMLCA GRWTGGKSTC SGDSGGPLVC NGVLQGITSW GSEPCALPER PSLYTKVVHY RKWIKDTIVA NP

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

P07288

Internal Search Terms :

Seminin, Semenogelase, PSA, Prostate-specific antigen isoform 1, Prostate-specific antigen, Prostate specific antigen isoform 1, Prostate specific antigen, P-30 antigen, P30 antigen, KLK3, KLK2A1, Kallikrein-3, Kallikrein3, Kallikrein related peptidase 3, Kallikrein 3, hK3, Gamma-seminoprotein, APS, Gamma seminoprotein, ATGP1566-10ug, ATGP1566-20ug, ATGP1566-50ug, ATGP1566-100ug, ATGP1566-250ug, ATGP1566-500ug, ATGP1566-1mg, ATGP1566-010, ATGP1566-020, ATGP1566-050, ATGP1566-100, ATGP1566-250, ATGP1566-500, ATGP1566-01M

more info or order :

NKMAX product webpage