product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant human eIF-4H/EIF4H protein
catalog :
ATGP1562
quantity :
20 ug
price :
105 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant human eIF-4H/EIF4H protein
Domain :
1-248aa
Catalog number (SKU) :
ATGP1562
NCBI :
NP_071496
Description :
Eukaryotic translation initiation factor 4H, also known as EIF4H, is a 248 amino acid protein that localizes to the perinuclear region of the cytoplasm and is expressed as two isoforms, designated short and long. EIF4H induces the RNA-dependent ATP hydrolysis catalyzed by the initiation factors EIF4A and EIF4B. EIF4H was further shown to stimulate the initial rate and extent of EIF4A-mediated mRNA secondary structure unwinding. Defects in the gene encoding EIF4H are associated with Williams- Beuren syndrome (WBS), a rare developmental disorder characterized by cardiovascular and musculo-skeletal abnormalities. Recombinant human EIF4H protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Alternative Names :
Eukaryotic translation initiation factor 4H, eIF-4H, WBSCR1, WSCR1, Williams-Beuren syndrome chromosome region 1
Concentration :
0.5mg/ml (determined by Bradford assay)
Formulation :
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 50% glycerol, 2mM DTT
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Richter Cook N J., et al. (1998) J Biol Chem. 273:7579-7587.;; Doepker R C., et al. (2004) J Virol. 78: 4684-4699.
Purity :
> 90% by SDS-PAGE
Applications :
SDS-PAGE
Antigen Species :
Human
Gene Category :
Epigenomics (Transcription & Translation)
Molecular Weight :
29.9 kDa (272aa) confirmed by MALDI-TOF
Amino Acid Sequence :
MADFDT YDDRAYSSFG GGRGSRGSAG GHGSRSQKEL PTEPPYTAYV GNLPFNTVQG DIDAIFKDLS IRSVRLVRDK DTDKFKGFCY VEFDEVDSLK EALTYDGALL GDRSLRVDIA EGRKQDKGGF GFRKGGPDDR GMGSSRESRG GWDSRDDFNS GFRDDFLGGR GGSRPGDRRT GPPMGSRFRD GPPLRGSNMD FREPTEEERA QRPRLQLKPR TVATPLNQVA NPNSAIFGGA RPREEVVQKE QE
Tag :
His-Tag
Expression System :
E.coli
Product Type Name :
Recombinant Protein
UniProt No. :
Q15056
Internal Search Terms :
EIF4H, Eukaryotic translation initiation factor 4H, eIF-4H, WBSCR1, WSCR1,ATGP1562-10ug,ATGP1562-20ug,ATGP1562-50ug,ATGP1562-100ug,ATGP1562-250ug,ATGP1562-500ug,ATGP1562-1mg,ATGP1562-10,ATGP1562-20,ATGP1562-50,ATGP1562-100,ATGP1562-250,ATGP1562-500,ATGP1562-1
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.