product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant human PQBP1 protein
catalog :
ATGP1540
quantity :
20 ug
price :
80 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant human PQBP1 protein
Domain :
1-265aa
Catalog number (SKU) :
ATGP1540
NCBI :
NP_005701.1
Description :
Polyglutamine binding protein 1, also known as PQBP1, is a transcription repressor that associates with polyglutamine tract-containing transcription regulators and causative genes for neurodegenerative disorders. PQBP-1 localizes to the nucleus and is present in neurons throughout the brain, with abundant levels in hippocampus, cerebellar cortex and olfactory bulb. PQBP-1 contains a WWP/WW domain that binds proline-rich motifs and a C2 domain that can influence Ca2+-dependent phospholipid signaling. Recombinant human PQBP1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Alternative Names :
Polyglutamine binding protein 1, MRX55, MRXS3, MRXS8, NPW38, RENS1, SHS
Concentration :
0.5mg/ml (determined by Bradford assay)
Formulation :
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 20% glycerol, 1mM DTT
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Waragai M., et al. (1999) Hum Mol Genet. 8:977-987.;; Waragai M C., et al. (2000) Biochem Biophys Res. 273: 592-595.
Purity :
> 90% by SDS-PAGE
Applications :
SDS-PAGE
Antigen Species :
Human
Gene Category :
Metabolism
Molecular Weight :
33 kDa (289aa) confirmed by MALDI-TOF
Amino Acid Sequence :
MPLPVA LQTRLAKRGI LKHLEPEPEE EIIAEDYDDD PVDYEATRLE GLPPSWYKVF DPSCGLPYYW NADTDLVSWL SPHDPNSVVT KSAKKLRSSN ADAEEKLDRS HDKSDRGHDK SDRSHEKLDR GHDKSDRGHD KSDRDRERGY DKVDRERERD RERDRDRGYD KADREEGKER RHHRREELAP YPKSKKAVSR KDEELDPMDP SSYSDAPRGT WSTGLPKRNE AKTGADTTAA GPLFQQRPYP SPGAVLRANA EASRTKQQD
Tag :
His-Tag
Expression System :
E.coli
Product Type Name :
Recombinant Protein
UniProt No. :
O60828
Internal Search Terms :
PQBP1, Polyglutamine binding protein 1, MRX55, MRXS3, MRXS8, NPW38, RENS1, SHS,ATGP1540-10ug,ATGP1540-20ug,ATGP1540-50ug,ATGP1540-100ug,ATGP1540-250ug,ATGP1540-500ug,ATGP1540-1mg,ATGP1540-10,ATGP1540-20,ATGP1540-50,ATGP1540-100,ATGP1540-250,ATGP1540-500,ATGP1540-1
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.