product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant human TCEA1 protein
catalog :
ATGP1534
quantity :
20 ug
price :
80 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant human TCEA1 protein
Domain :
1-301aa
Catalog number (SKU) :
ATGP1534
NCBI :
NP_006747
Description :
TCEA1 (Transcription elongation factor A protein 1) belongs to the TFS-II family. TCEA1 binds to Pol II and functions to cleave the nascent transcript, thereby unlocking the complex and allowing transcription to continue. Localized to the nucleus, TCEA1 contains three independently-folding domains, all of which are necessary for proper binding to Pol II. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus. Recombinant human TCEA1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Alternative Names :
Transcription elongation factor A protein 1, GTF2S, SII, TCEA, TF2S, TFIIS
Concentration :
1mg/ml (determined by Bradford assay)
Formulation :
Liquid in. 20mM Tris-HCl buffer (pH 7.5) containing 20% glycerol, 1mM DTT, 50mM NaCl
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Kulish, D. et al. (2001) Mol. Cell. Biol. 21: 4162-4168.;; Park H, et al. (1994) Gene 139 (2): 263-7.
Purity :
> 90% by SDS-PAGE
Applications :
SDS-PAGE
Antigen Species :
Human
Gene Category :
Epigenomics (Transcription & Translation)
Molecular Weight :
36.5 kDa (325aa) confirmed by MALDI-TOF
Amino Acid Sequence :
MGSSHHHHHH SSGLVPRGSH MGSHMEDEVV RFAKKMDKMV QKKNAAGALD LLKELKNIPM TLELLQSTRI GMSVNAIRKQ STDEEVTSLA KSLIKSWKKL LDGPSTEKDL DEKKKEPAIT SQNSPEAREE STSSGNVSNR KDETNARDTY VSSFPRAPST SDSVRLKCRE MLAAALRTGD DYIAIGADEE ELGSQIEEAI YQEIRNTDMK YKNRVRSRIS NLKDAKNPNL RKNVLCGNIP PDLFARMTAE EMASDELKEM RKNLTKEAIR EHQMAKTGGT QTDLFTCGKC KKKNCTYTQV QTRSADEPMT TFVVCNECGN RWKFC
Tag :
His-Tag
Expression System :
E.coli
Product Type Name :
Recombinant Protein
UniProt No. :
P23193
Internal Search Terms :
TCEA1, Transcription elongation factor A protein 1, GTF2S, SII, TCEA, TF2S, TFIIS,ATGP1534-10ug,ATGP1534-20ug,ATGP1534-50ug,ATGP1534-100ug,ATGP1534-250ug,ATGP1534-500ug,ATGP1534-1mg,ATGP1534-10,ATGP1534-20,ATGP1534-50,ATGP1534-100,ATGP1534-250,ATGP1534-500,ATGP1534-1
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.