Recombinant human Crystallin gamma C/CRYGC protein | NKMAX ATGP1529 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human Crystallin gamma C/CRYGC protein

catalog :

ATGP1529

quantity :

20 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human Crystallin gamma C/CRYGC protein

Domain :

1-174aa

Catalog number (SKU) :

ATGP1529

NCBI :

NP_066269

Description :

Gamma-crystallin C, also known as CRYGC, belongs to the beta/gamma-crystallin family. Mammalian lens crystallins are divided into alpha, beta, and gamma families; beta and gamma crystallins are also considered as a superfamily. Gamma-crystallins are a homogeneous group of highly symmetrical, monomeric proteins typically lacking connecting peptides and terminal extensions. They are differentially regulated after early development. Four gamma-crystallin genes (gamma-A through gamma-D) and three pseudogenes (gamma-E, gamma-F, gamma-G) are organized in a genomic segment as a gene cluster. Whether due to aging or mutations in specific genes, gamma-crystallins have been involved in cataract formation. Defects in CRYGC are a cause of cataract autosomal dominant (ADC) and cataract Coppock-like (CCL). Recombinant human CRYGC protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Alternative Names :

Gamma-crystallin C, CCL, CRYG3, Gamma-C-crystallin, Gamma-crystallin 2-1, Gamma-crystallin 3

Concentration :

1mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 2mM DTT, 200mM NaCl

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Slingsby C, et al. (2000) Eye (London, England) 13 (Pt 3b): 395-402. ;; Ren Z., et al. (2000) Hum. Genet. 106:531-537

Purity :

> 95% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Neuroscience

Molecular Weight :

23.4 kDa (198aa) confirmed by MALDI-TOF

Amino Acid Sequence :

MGKITF YEDRAFQGRS YETTTDCPNL QPYFSRCNSI RVESGCWMLY ERPNYQGQQY LLRRGEYPDY QQWMGLSDSI RSCCLIPQTV SHRLRLYERE DHKGLMMELS EDCPSIQDRF HLSEIRSLHV LEGCWVLYEL PNYRGRQYLL RPQEYRRCQD WGAMDAKAGS LRRVVDLY

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

P07315

Internal Search Terms :

CRYGC, Gamma-crystallin C, CCL, CRYG3,ATGP1529-10ug,ATGP1529-20ug,ATGP1529-50ug,ATGP1529-100ug,ATGP1529-250ug,ATGP1529-500ug,ATGP1529-1mg,ATGP1529-10,ATGP1529-20,ATGP1529-50,ATGP1529-100,ATGP1529-250,ATGP1529-500,ATGP1529-1

more info or order :

NKMAX product webpage