product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant human BCAT2 protein
catalog :
ATGP1523
quantity :
10 ug
price :
105 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant human BCAT2 protein
Domain :
28-392aa
Catalog number (SKU) :
ATGP1523
NCBI :
NP_001181
Description :
BCAT2 belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. This protein forms a dimer that catalyzes the first step in the production of the branched chain amino acids leucine, isoleucine, and valine. It may also function as a transporter of branched chain alpha-keto acids. Recombinant human BCAT2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Alternative Names :
Branched chain amino-acid aminotransferase 2 mitochondrial, Branched chain amino-acid aminotransferase 2, mitochondrial, BCAM, BCATM, BCT2, PP18, ECA40, Placental protein 18
Concentration :
0.5mg/ml (determined by Bradford assay)
Formulation :
Liquid in. 20mM Tris-HCl buffer (pH 7.5) containing 10% glycerol 0.2M NaCl, 1mM DTT
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Coles SJ. et al. (2009) Biochemistry Jan 27;;48(3):645-56.;; Yennawar N.H.et al. (2007) J. Biol. Chem. 281:39660-39671
Purity :
> 90% by SDS-PAGE
Applications :
SDS-PAGE
Antigen Species :
Human
Gene Category :
Metabolism
Molecular Weight :
43.9 kDa (390aa) confirmed by MALDI-TOF
Amino Acid Sequence :
ASSSF KAADLQLEMT QKPHKKPGPG EPLVFGKTFT DHMLMVEWND KGWGQPRIQP FQNLTLHPAS SSLHYSLQLF EGMKAFKGKD QQVRLFRPWL NMDRMLRSAM RLCLPSFDKL ELLECIRRLI EVDKDWVPDA AGTSLYVRPV LIGNEPSLGV SQPTRALLFV ILCPVGAYFP GGSVTPVSLL ADPAFIRAWV GGVGNYKLGG NYGPTVLVQQ EALKRGCEQV LWLYGPDHQL TEVGTMNIFV YWTHEDGVLE LVTPPLNGVI LPGVVRQSLL DMAQTWGEFR VVERTITMKQ LLRALEEGRV REVFGSGTAC QVCPVHRILY KDRNLHIPTM ENGPELILRF QKELKEIQYG IRAHEWMFPV
Tag :
His-Tag
Expression System :
E.coli
Product Type Name :
Recombinant Protein
UniProt No. :
O15382
Internal Search Terms :
BCAT2, Branched chain amino-acid aminotransferase 2 mitochondrial, Branched chain amino-acid aminotransferase 2, mitochondrial, BCAM, BCATM, BCT2, PP18,ATGP1523-10ug,ATGP1523-20ug,ATGP1523-50ug,ATGP1523-100ug,ATGP1523-250ug,ATGP1523-500ug,ATGP1523-1mg,ATGP1523-10,ATGP1523-20,ATGP1523-50,ATGP1523-100,ATGP1523-250,ATGP1523-500,ATGP1523-1
References with this Product :
Günther J, et al. BAY-069, a Novel (Trifluoromethyl)pyrimidinedione-Based BCAT1/2 Inhibitor and Chemical Probe. (J Med Chem. 2022){https://pubmed.ncbi.nlm.nih.gov/36261130/}
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.