Recombinant human MEK2 protein | NKMAX ATGP1520 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human MEK2 protein

catalog :

ATGP1520

quantity :

10 ug

price :

240 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human MEK2 protein

Domain :

1-400aa

Catalog number (SKU) :

ATGP1520

NCBI :

NP_109587

Description :

MAP2K2, also known as MEK2, belongs to the STE grouping of kinases. Both MEK2 and the related MEK1 are dualspecificity kinases, phosphorylating and activating the mitogen-activated protein kinases ERK1 and ERK2 at T and Y positions within the phosphoacceptor sequence T-E-Y. MAP2K2 is activated by a wide variety of growth factors and cytokines and also by membrane depolarization and calcium influx. Recombinant human MAP2K2 proetin, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Alternative Names :

Mitogen-activated protein kinase kinase 2, MAP kinase kinase 2, MAPKK2, MAPK/ERK kinase 2, MEK2, MKK2, PRKMK2, ERK activator kinase 2

Concentration :

0.25mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 10% glycerol

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Crews C M., et al. (1992) Science. 258:478-480.;; Rosen L B., et al. (1994) Neuron. 12: 1207-1221.

Purity :

> 90% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Cancer

Molecular Weight :

46.9 kDa (424aa) confirmed by MALDI-TOF

Amino Acid Sequence :

MLARRK PVLPALTINP TIAEGPSPTS EGASEANLVD LQKKLEELEL DEQQKKRLEA FLTQKAKVGE LKDDDFERIS ELGAGNGGVV TKVQHRPSGL IMARKLIHLE IKPAIRNQII RELQVLHECN SPYIVGFYGA FYSDGEISIC MEHMDGGSLD QVLKEAKRIP EEILGKVSIA VLRGLAYLRE KHQIMHRDVK PSNILVNSRG EIKLCDFGVS GQLIDSMANS FVGTRSYMAP ERLQGTHYSV QSDIWSMGLS LVELAVGRYP IPPPDAKELE AIFGRPVVDG EEGEPHSISP RPRPPGRPVS GHGMDSRPAM AIFELLDYIV NEPPPKLPNG VFTPDFQEFV NKCLIKNPAE RADLKMLTNH TFIKRSEVEE VDFAGWLCKT LRLNQPGTPT RTAV

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

P36507

Internal Search Terms :

PRKMK-2, PRKMK2, PRKMK 2, MKK-2, MKK2, MKK 2, Mitogen-activated protein kinase kinase 2, Mitogen activated protein kinase kinase 2, MEK-2, MEK2, MEK 2, MAPKK-2, MAPKK2, MAPKK 2, MAPK/ERK kinase 2, MAP2K2, MAP kinase kinase 2, ERK activator kinase 2, Dual specificity mitogen-activated protein kinase kinase 2, Dual specificity mitogen activated protein kinase kinase 2, CFC4, ATGP1520-10ug, ATGP1520-20ug, ATGP1520-50ug, ATGP1520-100ug, ATGP1520-250ug, ATGP1520-500ug, ATGP1520-1mg, ATGP1520-010, ATGP1520-020, ATGP1520-050, ATGP1520-100, ATGP1520-250, ATGP1520-500, ATGP1520-01M

more info or order :

NKMAX product webpage