Recombinant human IL-12 p40 protein | NKMAX ATGP1483 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human IL-12 p40 protein

catalog :

ATGP1483

quantity :

10 ug

price :

105 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human IL-12 p40 protein

Domain :

23-328aa

Catalog number (SKU) :

ATGP1483

NCBI :

NP_002178

Description :

IL12P40 (interleukin 12 subunit beta), also known as natural killer cell stimulatory factor 2, or cytotoxic lymphocyte maturation factor 2, p40, belongs to the type I cytokine receptor family. This protein is a cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. Interleukin 12 is a disulfide-linked heterodimer composed of the 40 kD cytokine receptor like subunit encoded by this gene, and a 35 kD subunit encoded by IL12A. This cytokine is expressed by activated macrophages that serve as an essential inducer of Th1 cells development. Recombinant human IL12P40 protein, fused to His-tag at C-terminus, was expressed in Hi-5 cell using baculovirus expression system and purified by using conventional chromatography.

Alternative Names :

Interleukin 12B, Interleukin-12 beta chain, IL-12B, Cytotoxic lymphocyte maturation factor 40 kDa subunit, CLMF p40, IL-12 subunit p40, interleukin 12 p40, NK cell stimulatory factor chain 2, NKSF2, CLMF2

Concentration :

0.25mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 2mM DTT, 20% glycerol, 100mM NaCl, 0.1mM PMSF

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Oppmann B., et al (2000) Immunity 13:715-725(2000);; Presky et al. (1996) Proc. Natl. Acad. Sci. u.S.A. 93 (24): 14002-7.

Purity :

> 90% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Hormones & Cytokines

Molecular Weight :

35.8 kDa (315aa)

Endotoxin :

< 1 EU per 1ug of protein (determined by LAL method)

Amino Acid Sequence :

ADPIWELKKD VYVVELDWYP DAPGEMVVLT CDTPEEDGIT WTLDQSSEVL GSGKTLTIQV KEFGDAGQYT CHKGGEVLSH SLLLLHKKED GIWSTDILKD QKEPKNKTFL RCEAKNYSGR FTCWWLTTIS TDLTFSVKSS RGSSDPQGVT CGAATLSAER VRGDNKEYEY SVECQEDSAC PAAEESLPIE VMVDAVHKLK YENYTSSFFI RDIIKPDPPK NLQLKPLKNS RQVEVSWEYP DTWSTPHSYF SLTFCVQVQG KSKREKKDRV FTDKTSATVI CRKNASISVR AQDRYYSSSW SEWASVPCSH HHHHH

Tag :

His-Tag

Expression System :

Baculovirus

Product Type Name :

Recombinant Protein

UniProt No. :

P29460

Internal Search Terms :

IL12B, IL12 p40, interleukin 12 subuit beta, CLMF, NKSF, CLMF2, NKSF2, IL-12B,ATGP1483-10ug,ATGP1483-20ug,ATGP1483-50ug,ATGP1483-100ug,ATGP1483-250ug,ATGP1483-500ug,ATGP1483-1mg,ATGP1483-10,ATGP1483-20,ATGP1483-50,ATGP1483-100,ATGP1483-250,ATGP1483-500,ATGP1483-1

more info or order :

NKMAX product webpage