product summary
Loading...
company name :
NKMAX
product type :
protein
product name :
Recombinant human Ornithine Carbamoyltransferase/OTC protein
catalog :
ATGP1473
quantity :
10 ug
price :
105 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant human Ornithine Carbamoyltransferase/OTC protein
Domain :
33-354aa
Catalog number (SKU) :
ATGP1473
NCBI :
NP_000522.3
Description :
OTC, also called ornithine carbamoyltransferase, belongs to the ATCase/OTCase family. OTC plays a vital role in the urea cycle, catalyzing the second step in this pathway: the formation of L-citrulline from L-orthinine and carbamoyl phosphate. In humans, the urea cycle is an important pathway to detoxification of ammonia. Mutations in the gene encoding OTC are associated with the X-linked disorder OTCD (ornithine carbamoyltransferase deficiency). OTCD is a disorder of the urea cycle characterized by hyperammonemia. Recombinant human OTC protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Alternative Names :
ornithine carbamoyltransferase, OCTD, OTCase
Concentration :
0.5mg/ml (determined by Bradford assay)
Formulation :
Liquid in. 20mM MES buffer (pH 6.0) containing 2mM DTT, 10% glycerol, 100mM NaCl
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Trivedi, M., et al. (2001) J. Clin. Gastroenterol. 32: 340-343.;; Yamaguchi, S., et al. (2006) Hum. Mutat. 27: 626-632.
Purity :
> 95% by SDS-PAGE
Applications :
SDS-PAGE
Antigen Species :
Human
Gene Category :
Metabolism
Molecular Weight :
38.9 kDa (347aa) confirmed by MALDI-TOF
Amino Acid Sequence :
NKVQL KGRDLLTLKN FTGEEIKYML WLSADLKFRI KQKGEYLPLL QGKSLGMIFE KRSTRTRLST ETGFALLGGH PCFLTTQDIH LGVNESLTDT ARVLSSMADA VLARVYKQSD LDTLAKEASI PIINGLSDLY HPIQILADYL TLQEHYSSLK GLTLSWIGDG NNILHSIMMS AAKFGMHLQA ATPKGYEPDA SVTKLAEQYA KENGTKLLLT NDPLEAAHGG NVLITDTWIS MGQEEEKKKR LQAFQGYQVT MKTAKVAASD WTFLHCLPRK PEEVDDEVFY SPRSLVFPEA ENRKWTIMAV MVSLLTDYSP QLQKPKF
Tag :
His-Tag
Expression System :
E.coli
Product Type Name :
Recombinant Protein
UniProt No. :
P00480
Internal Search Terms :
Ornithine Carbamoyltransferase, OTC, ornithine carbamoyltransferase, OCTD, OTCase,ATGP1473-10ug,ATGP1473-20ug,ATGP1473-50ug,ATGP1473-100ug,ATGP1473-250ug,ATGP1473-500ug,ATGP1473-1mg,ATGP1473-10,ATGP1473-20,ATGP1473-50,ATGP1473-100,ATGP1473-250,ATGP1473-500,ATGP1473-1
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.