product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant human CARD18 protein
catalog :
ATGP1460
quantity :
10 ug
price :
105 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant human CARD18 protein
Domain :
1-90aa
Catalog number (SKU) :
ATGP1460
NCBI :
NP_067546
Description :
Caspase recruitment domain-containing protein 18, also known as CARD18, is a member of the death-domain-fold superfamily that is induced by proinflammatory stimuli. It consists essentially only of a CARD, inhibits generation of IL-1b by interacting with caspase-1 and preventing association with RIP 2. The association of CARD18 with caspase-1 is facilitated by the charge-charge interactions between the prodomain of caspase-1 and the surface charge of CARD18. Recombinant human CARD18 proetin, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Alternative Names :
Caspase recruitment domain-containing protein 18, ICEBERG, pseudo-ICE, uNQ5804
Concentration :
0.5mg/ml (determined by Bradford assay)
Formulation :
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT,10% glycerol, 0.1M NaCl
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Humke E W., et al. (2000) Cell. 103:99-111.;; Watson R W., et al. (1998) J Immunol. 161:957-962
Purity :
> 95% by SDS-PAGE
Applications :
SDS-PAGE
Antigen Species :
Human
Gene Category :
Apoptosis
Molecular Weight :
12.3 kDa (110aa) confirmed by MALDI-TOF
Amino Acid Sequence :
MGSSHHHHHH SSGLVPRGSH MADQLLRKKR RIFIHSVGAG TINALLDCLL EDEVISQEDM NKVRDENDTV MDKARVLIDL VTGKGPKSCC KFIKHLCEED PQLASKMGLH
Tag :
His-Tag
Expression System :
E.coli
Product Type Name :
Recombinant Protein
UniProt No. :
P57730
Internal Search Terms :
CARD18, Caspase recruitment domain-containing protein 18, ICEBERG, pseudo-ICE, uNQ5804,ATGP1460-10ug,ATGP1460-20ug,ATGP1460-50ug,ATGP1460-100ug,ATGP1460-250ug,ATGP1460-500ug,ATGP1460-1mg,ATGP1460-10,ATGP1460-20,ATGP1460-50,ATGP1460-100,ATGP1460-250,ATGP1460-500,ATGP1460-1
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.