product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant human TIFA protein
catalog :
ATGP1414
quantity :
10 ug
price :
105 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant human TIFA protein
Domain :
1-184aa
Catalog number (SKU) :
ATGP1414
NCBI :
NP_443096.1
Description :
TIFA, also known as TRAF-interacting protein with FHA domain-containing protein A, is an adapter protein which mediates the IRAK1 and TRAF6 interaction following IL-1 stimulation, resulting in the downstream activation of NF-kappa-B and AP-1 pathways. This protein induces the oligomerization and polyubiquitination of TRAF6, which leads to the activation of TAK1 and IKK through a proteasome-independent mechanism. Recombinant human TIFA protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.
Alternative Names :
TRAF-interacting protein with FHA domain-containing protein A, T2BP, T6BP, TIFAA
Concentration :
0.5mg/ml (determined by Bradford assay)
Formulation :
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 20% glycerol, 1mM DTT
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Takatsuna H., et al. (2003) J. Biol. Chem. 278:12144-12150;; Ea C.-K., et al. (2004) Proc. Natl. Acad. Sci. u.S.A. 101:15318-15323
Purity :
> 90% by SDS-PAGE
Applications :
SDS-PAGE
Antigen Species :
Human
Gene Category :
Signal Transduction
Molecular Weight :
24.0 kDa (208aa) confirmed by MALDI-TOF
Amino Acid Sequence :
MTSFED ADTEETVTCL QMTVYHPGQL QCGIFQSISF NREKLPSSEV VKFGRNSNIC HYTFQDKQVS RVQFSLQLFK KFNSSVLSFE IKNMSKKTNL IVDSRELGYL NKMDLPYRCM VRFGEYQFLM EKEDGESLEF FETQFILSPR SLLQENNWPP HRPIPEYGTY SLCSSQSSSP TEMDENES
Tag :
His-Tag
Expression System :
E.coli
Product Type Name :
Recombinant Protein
UniProt No. :
Q96CG3
Internal Search Terms :
TIFA, TRAF-interacting protein with FHA domain-containing protein A, T2BP, T6BP, TIFAA,ATGP1414-10ug,ATGP1414-20ug,ATGP1414-50ug,ATGP1414-100ug,ATGP1414-250ug,ATGP1414-500ug,ATGP1414-1mg,ATGP1414-10,ATGP1414-20,ATGP1414-50,ATGP1414-100,ATGP1414-250,ATGP1414-500,ATGP1414-1
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.