product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant human TRAM/TICAM2 protein
catalog :
ATGP1402
quantity :
10 ug
price :
80 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant human TRAM/TICAM2 protein
Domain :
1-235aa
Catalog number (SKU) :
ATGP1402
NCBI :
NP_067681.1
Description :
Toll TIR domain-containing adapter molecule 2, also known as TICAM2, is a member of the Toll/interleukin-1 receptor (TIR) family, a group of proteins that include the Toll-like receptors (TLRs). TICAM-2, a cytoplasmic protein, physically bridges TLR4 and TICAM-1 and functionally transmits LPS-TLR4 signaling to TICAM-1, which in turn activates IRF-3. It is involved in IL1-triggered NF-kappa-B activation, functioning upstream of IRAK1, IRAK2, TRAF6, and IKBKB. Recombinant human TICAM2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Alternative Names :
TIR domain-containing adapter molecule 2, TICAM-2, TIRAP3, TIRP, TRAM
Concentration :
1mg/ml (determined by Bradford assay)
Formulation :
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 10% glycerol, 0.1M NaCl
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Yamamoto M., et al. (2002) J Immunol. 169:6668-6672.;; Oshiumi H., et al. (2003) J Biol Chem. 278:49751-49762.
Purity :
> 85% by SDS-PAGE
Applications :
SDS-PAGE
Antigen Species :
Human
Gene Category :
Immunology
Molecular Weight :
29.4 kDa (259aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)
Amino Acid Sequence :
MGIGKS KINSCPLSLS WGKRHSVDTS PGYHESDSKK SEDLSLCNVA EHSNTTEGPT GKQEGAQSVE EMFEEEAEEE VFLKFVILHA EDDTDEALRV QNLLQDDFGI KPGIIFAEMP CGRQHLQNLD DAVNGSAWTI LLLTENFLRD TWCNFQFYTS LMNSVNRQHK YNSVIPMRPL NNPLPRERTP FALQTINALE EESRGFPTQV ERIFQESVYK TQQTIWKETR NMVQRQFIA
Tag :
His-Tag
Expression System :
E.coli
Product Type Name :
Recombinant Protein
UniProt No. :
Q86XR7
Internal Search Terms :
TICAM2, TIR domain-containing adapter molecule 2, TICAM-2, TIRAP3, TIRP, TRAM,ATGP1402-10ug,ATGP1402-20ug,ATGP1402-50ug,ATGP1402-100ug,ATGP1402-250ug,ATGP1402-500ug,ATGP1402-1mg,ATGP1402-10,ATGP1402-20,ATGP1402-50,ATGP1402-100,ATGP1402-250,ATGP1402-500,ATGP1402-1
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.