protein

Recombinant human FGF-10 protein

ATGP1387

10 ug

105 USD

Recombinant human FGF-10 protein

38-208aa

ATGP1387

NP_004456.1

FGF10, also known as fibroblast growth factor 10, exhibits mitogenic activity for keratinizing epidermal cells, but essentially no activity for fibroblasts, which is similar to the biological activity of FGF7. Studies of the mouse homolog of suggested that this gene is required for embryonic epidermal morphogenesis including brain development, lung morphogenesis, and initiation of lim bud formation. FGF10 is also implicated to be a primary factor in the process of wound healing. Recombinant human FGF10 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.

Fibroblast growth factor 10, Keratinocyte growth factor 2

0.25mg/ml (determined by Bradford assay)

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 50% glycerol, 0.2M NaCl, 2mM DTT, 2mM EDTA

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Entesarian M., et al. (2005) Nat. Genet. 37:125-127;; Milunsky J.M., et al. (2006) Clin. Genet. 69:349-354

> 95% by SDS-PAGE

SDS-PAGE

Human

Growth factors

22.0 kDa (196aa) confirmed by MALDI-TOF

< 1 EU per 1ug of protein (determined by LAL method)

QALGQ DMVSPEATNS SSSSFSSPSS AGRHVRSYNH LQGDVRWRKL FSFTKYFLKI EKNGKVSGTK KENCPYSILE ITSVEIGVVA VKAINSNYYL AMNKKGKLYG SKEFNNDCKL KERIEENGYN TYASFNWQHN GRQMYVALNG KGAPRRGQKT RRKNTSAHFL PMVVHS

His-Tag

E.coli

Recombinant Protein

O15520

FGF10, Fibroblast growth factor 10, Keratinocyte growth factor 2,ATGP1387-10ug,ATGP1387-20ug,ATGP1387-50ug,ATGP1387-100ug,ATGP1387-250ug,ATGP1387-500ug,ATGP1387-1mg,ATGP1387-10,ATGP1387-20,ATGP1387-50,ATGP1387-100,ATGP1387-250,ATGP1387-500,ATGP1387-1

Jee JH, et al. Development of Collagen-Based 3D Matrix for Gastrointestinal Tract-Derived Organoid Culture. (Stem Cells Int. 2019){https://pubmed.ncbi.nlm.nih.gov/31312220/};;Park E, et al. Development of organoid-based drug metabolism model. (Toxicol Appl Pharmacol. 2019){https://pubmed.ncbi.nlm.nih.gov/31678242/};;Kim HK, et al. Generation of tonsil organoids as an ex vivo model for SARS-CoV-2 infection. (bioRxiv. 2020){https://doi.org/10.1101/2020.08.06.239574};;Kim HK, et al. Generation of human tonsil epithelial organoids as an ex vivo model for SARS-CoV-2 infection. (Biomaterials. 2022){https://pubmed.ncbi.nlm.nih.gov/35286852/};;Go YH, et al. Modeling Pancreatic Cancer with Patient-Derived Organoids Integrating Cancer-Associated Fibroblasts. (Cancers (Basel). 2022){https://pubmed.ncbi.nlm.nih.gov/35565206/};;Lim JY, et al. Human Palatine Tonsils Are Linked to Alzheimers Disease through Function of Reservoir of Amyloid Beta Protein Associated with Bacterial Infection. (Cells. 2022){https://pubmed.ncbi.nlm.nih.gov/35892582/}