product summary
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company name :
NKMAX
product type :
protein
product name :
Recombinant human p18INK4c/CDKN2C protein
catalog :
ATGP1377
quantity :
20 ug
price :
80 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant human p18INK4c/CDKN2C protein
Domain :
1-168aa
Catalog number (SKU) :
ATGP1377
NCBI :
NP_001253
Description :
CDKN2C (Cyclin-dependent kinase 4 inhibitor C ) belongs to the CDKN2 cyclin-dependent kinase inhibitor family. It has been shown to interact with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. And this protein suppresses the cell growth and proliferation with a correlated dependence on endogenous retinoblastoma protein RB. Studies in the knockout mice suggested the roles of this gene in regulating spermatogenesis, as well as in suppressing tumorigenesis. Recombinant human CDKN2C protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Alternative Names :
Cyclin-dependent kinase 4 inhibitor C, INK4C, p18, p18-INK4C
Concentration :
0.5mg/ml (determined by Bradford assay)
Formulation :
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 2mM DTT, 10% glycerol, 200mM NaCl
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Blais A, et al. (1998).) Biochem Biophys Res Commun 247 (1): 146-53.;; Serrano M, et al. (1994). Nature 366 (6456): 704-7.
Purity :
> 95% by SDS-PAGE
Applications :
SDS-PAGE
Antigen Species :
Human
Gene Category :
Cancer
Molecular Weight :
20.7 kDa (192aa) confirmed by MALDI-TOF
Amino Acid Sequence :
MGSSHHHHHH SSGLVPRGSH MGSHMAEPWG NELASAAARG DLEQLTSLLQ NNVNVNAQNG FGRTALQVMK LGNPEIARRL LLRGANPDLK DRTGFAVIHD AARAGFLDTL QTLLEFQADV NIEDNEGNLP LHLAAKEGHL RVVEFLVKHT ASNVGHRNHK GDTACDLARL YGRNEVVSLM QANGAGGATN LQ
Tag :
His-Tag
Expression System :
E.coli
Product Type Name :
Recombinant Protein
UniProt No. :
P42773
Internal Search Terms :
p18INK4CDKN2C, Cyclin-dependent kinase 4 inhibitor C, INK4C, p18, p18-INK4C,ATGP1377-10ug,ATGP1377-20ug,ATGP1377-50ug,ATGP1377-100ug,ATGP1377-250ug,ATGP1377-500ug,ATGP1377-1mg,ATGP1377-10,ATGP1377-20,ATGP1377-50,ATGP1377-100,ATGP1377-250,ATGP1377-500,ATGP1377-1
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.