Recombinant human RACK1 protein | NKMAX ATGP1375 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human RACK1 protein

catalog :

ATGP1375

quantity :

10 ug

price :

105 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human RACK1 protein

Domain :

1-317aa

Catalog number (SKU) :

ATGP1375

NCBI :

NP_006089.1

Description :

GNB2L1 was originally identified as an anchoring protein for protein kinase C beta (PKCbeta), which it stabilises in the active state and anchors to membranes or functional sites. However, evidence has accumulated to support a central role of GNB2L1 in critical biological responses. In addition to binding specifically to the active form of PKCbeta isoforms, GNB2L1 also interacts with several other important signaling proteins including the Src kinase family, integrin beta1, integrin beta2, integrin beta3 and integrin beta5, beta-spectrin and dynamin, RasGAP, the androgen receptor, insulin-like growth factor 1 receptor (IGF-1r), Epstein-Barr virus trans-activator protein BZLF1, p73 and pRB. GNB2L1 is ubiquitously expressed in the tissues of higher mammals and humans including brain, liver, and spleen. Recombinant human GNB2L1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography.

Alternative Names :

Guanine nucleotide-binding protein subunit beta-2-like 1, Guanine nucleotide-binding protein subunit beta-2-like 1, Gnb2-rs1, H12.3, HLC-7, PIG21, RACK1

Concentration :

0.25mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 50% glycerol, 0.2M NaCl, 5mM DTT

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Chang B.Y., et al. (1998) Mol. Cell. Biol. 18:3245-3256;; Chang B.Y., et al. (2001) J. Biol. Chem. 276:20346-20356

Purity :

> 95% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Signal Transduction

Molecular Weight :

37.2 kDa (337aa) confirmed by MALDI-TOF

Amino Acid Sequence :

MTEQMTLRGT LKGHNGWVTQ IATTPQFPDM ILSASRDKTI IMWKLTRDET NYGIPQRALR GHSHFVSDVV ISSDGQFALS GSWDGTLRLW DLTTGTTTRR FVGHTKDVLS VAFSSDNRQI VSGSRDKTIK LWNTLGVCKY TVQDESHSEW VSCVRFSPNS SNPIIVSCGW DKLVKVWNLA NCKLKTNHIG HTGYLNTVTV SPDGSLCASG GKDGQAMLWD LNEGKHLYTL DGGDIINALC FSPNRYWLCA ATGPSIKIWD LEGKIIVDEL KQEVISTSSK AEPPQCTSLA WSADGQTLFA GYTDNLVRVW QVTIGTR

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

P63244

Internal Search Terms :

RACK1, Guanine nucleotide-binding protein subunit beta-2-like 1, Guanine nucleotide-binding protein subunit beta-2-like 1, Gnb2-rs1, H12.3, HLC-7, PIG21, RACK1,ATGP1375-10ug,ATGP1375-20ug,ATGP1375-50ug,ATGP1375-100ug,ATGP1375-250ug,ATGP1375-500ug,ATGP1375-1mg,ATGP1375-10,ATGP1375-20,ATGP1375-50,ATGP1375-100,ATGP1375-250,ATGP1375-500,ATGP1375-1

more info or order :

NKMAX product webpage