Recombinant human TPM3 protein | NKMAX ATGP1368 product information

product summary

company name :

NKMAX

product type :

protein

product name :

Recombinant human TPM3 protein

catalog :

ATGP1368

quantity :

10 ug

price :

80 USD

more info or order :

NKMAX product webpage

product information

Product Type :

Proteins

Item Name :

Recombinant human TPM3 protein

Domain :

1-248aa

Catalog number (SKU) :

ATGP1368

NCBI :

NP_705935.1

Description :

Tropomyosin alpha-3 chain, also known as TPM3, is member of the tropomyosin family of actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosins are dimers of coiled-coil proteins that polymerize end-to-end along the major groove in most actin filaments. They provide stability to the filaments and regulate access of other actin-binding proteins. Mutations in this gene result in autosomal dominant nemaline myopathy, and oncogenes formed by chromosomal translocations involving this locus are associated with cancer. Recombinant human TPM3 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Alternative Names :

Tropomyosin alpha-3 chain, hscp30, NEM1, OK/SW-cl.5, TM-5, TM3, TM30 TM30nm, TPMsk, TRK

Concentration :

0.5mg/ml (determined by Bradford assay)

Formulation :

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 20% glycerol, 0.1M NaCl

Storage :

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

General References :

Ohtsuki I., et al. (2002) J Biochem. 131:739-743.;; Tiso N., et al. (1997) Biochem Biophys Res Commun. 230:347-350.

Purity :

> 85% by SDS-PAGE

Applications :

SDS-PAGE

Antigen Species :

Human

Gene Category :

Cytoskeleton

Molecular Weight :

31.6 kDa (272aa) confirmed by MALDI-TOF

Amino Acid Sequence :

MAGITT IEAVKRKIQV LQQQADDAEE RAERLQREVE GERRAREQAE AEVASLNRRI QLVEEELDRA QERLATALQK LEEAEKAADE SERGMKVIEN RALKDEEKME LQEIQLKEAK HIAEEADRKY EEVARKLVII EGDLERTEER AELAESRCRE MDEQIRLMDQ NLKCLSAAEE KYSQKEDKYE EEIKILTDKL KEAETRAEFA ERSVAKLEKT IDDLEDKLKC TKEEHLCTQR MLDQTLLDLN EM

Tag :

His-Tag

Expression System :

E.coli

Product Type Name :

Recombinant Protein

UniProt No. :

P06753

Internal Search Terms :

TPM3, Tropomyosin alpha-3 chain, hscp30, NEM1, OK/SW-cl.5, TM-5, TM3, TM30 TM30nm, TPMsk, TRK,ATGP1368-10ug,ATGP1368-20ug,ATGP1368-50ug,ATGP1368-100ug,ATGP1368-250ug,ATGP1368-500ug,ATGP1368-1mg,ATGP1368-10,ATGP1368-20,ATGP1368-50,ATGP1368-100,ATGP1368-250,ATGP1368-500,ATGP1368-1

more info or order :

NKMAX product webpage