product summary
Loading...
company name :
NKMAX
product type :
protein
product name :
Recombinant human PTPMT1 protein
catalog :
ATGP1353
quantity :
20 ug
price :
105 USD
more info or order :
product information
Product Type :
Proteins
Item Name :
Recombinant human PTPMT1 protein
Domain :
28-201aa
Catalog number (SKU) :
ATGP1353
NCBI :
NP_783859.1
Description :
PTPMT1 (protein tyrosine phosphatase mitochondrial 1), also known as MOSP or PLIP (phosphoinositide lipid phosphatase) and previously known as DuSP23, is a widely expressed PTP membrane protein with high expression levels in pancreatic beta cells. This protein exclusively localizes to the matrix face of the inner membrane of the mitochondrion. It is responsible for dephosphorylating mitochondrial proteins and therefore plays a significant role in the production of ATP and secretion of insulin. For its substrate, PTPMT1 displays a specific preference for the lipid signaling molecule phosphatidylinositol 5-phosphate. Recombinant human PTPMT1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.
Alternative Names :
Potein tyrosine phosphatase mitochondrial 1, Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1, PTEN-like phosphatase, Phosphoinositide lipid phosphatase, MOSP, PLIP, DUSP23
Concentration :
1mg/ml (determined by Bradford assay)
Formulation :
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 1mM DTT, 0.15M NaCl.
Storage :
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
General References :
Pagliarini DJ., et al. (2005) Mol Cell. 19(2):197-207.;; Merlot S., et al. (2003) J Biol Chem. 278(41):39866-73.
Purity :
> 95% by SDS-PAGE
Applications :
SDS-PAGE
Antigen Species :
Human
Gene Category :
Enzymes & Proteases
Molecular Weight :
22.5 kDa (199aa) confirmed by MALDI-TOF
Amino Acid Sequence :
MGSSHHHHHH SSGLVPRGSH MGSHM>KVPGR AHRDWYHRID PTVLLGALPL RSLTRQLVQD ENVRGVITMN EEYETRFLCN SSQEWKRLGV EQLRLSTVDM TGIPTLDNLQ KGVQFALKYQ SLGQCVYVHC KAGRSRSATM VAAYLIQVHK WSPEEAVRAI AKIRSYIHIR PGQLDVLKEF HKQITARATK DGTFVISKT
Tag :
His-Tag
Expression System :
E.coli
Product Type Name :
Recombinant Protein
UniProt No. :
Q8WUK0
Internal Search Terms :
PTPMT1, Protein tyrosine phosphatase mitochondrial 1, Protein tyrosine phosphatase, mitochondrial 1, DuSP23, FLJ46081, MOSP, PLIP, PNAS-129,ATGP1353-10ug,ATGP1353-20ug,ATGP1353-50ug,ATGP1353-100ug,ATGP1353-250ug,ATGP1353-500ug,ATGP1353-1mg,ATGP1353-10,ATGP1353-20,ATGP1353-50,ATGP1353-100,ATGP1353-250,ATGP1353-500,ATGP1353-1
more info or order :
company information
NKMAX
SNUH Health Care Innovation Park 6F
172 Dolma-ro, Bundang-gu
Seongnam-si, Gyeonggi-do
https://www.nkmaxbio.com
82-31-8017-8114
headquarters: South Korea
NKMAX Co. Ltd. is a biotech company that manufactures and supplies a unique line of quality proteins and antibodies worldwide to both researchers and retailers.